Chlorella Vulgaris sh-Oligopeptide-1

INCI: CHLORELLA VULGARIS SH-OLIGOPEPTIDE-1

CAS Number
Not assigned
Function
Skin conditioning, skin protecting (EGF — Epidermal Growth Factor expressed in Chlorella vulgaris)
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes FDA — no specific restriction; sh-Oligopeptide-1 (EGF) widely used in K-beauty/cosmetics; not independently CIR-reviewed

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

EGF promotes cell proliferation — potential concern for use on damaged or compromised skin or pre-cancerous conditions; South Korea and EU assessors increasingly requesting proliferation assay data; GMO expression system documentation needed for EU market

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Concern Level: Moderate

Frequently Asked Questions

Is Chlorella Vulgaris sh-Oligopeptide-1 safe in cosmetics?

EGF promotes cell proliferation — potential concern for use on damaged or compromised skin or pre-cancerous conditions; South Korea and EU assessors increasingly requesting proliferation assay data; GMO expression system documentation needed for EU market The EU classifies Chlorella Vulgaris sh-Oligopeptide-1 as "permitted". Safety rating: MODERATE.

Is Chlorella Vulgaris sh-Oligopeptide-1 allowed in the EU?

Chlorella Vulgaris sh-Oligopeptide-1 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Chlorella Vulgaris sh-Oligopeptide-1 do in cosmetics?

Chlorella Vulgaris sh-Oligopeptide-1 functions as: Skin conditioning, skin protecting (EGF — Epidermal Growth Factor expressed in Chlorella vulgaris). It is classified as a cosmetic ingredient in our database. CAS number: Not assigned.

What is the Margin of Safety for Chlorella Vulgaris sh-Oligopeptide-1?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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