Is Chlorothymol safe in cosmetics?
Chlorothymol has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Chlorothymol
Also known as: 4-Chloro-2-isopropyl-5-methylphenol, 4-06-00-03344, BRN 2084453, Caswell No. 216, 4-Chloro-6-isopropyl-3-methylphenol (+8 more)
INCI: CHLOROTHYMOL
Chlorothymol (CAS 89-68-9) is a cosmetic cosmetic ingredient functioning as Preservative, denaturant, deodorizing agent, oral care agent. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 89-68-9 →
Auto-generated CPSR Part A draft with source citations
Function
Preservative, denaturant, deodorizing agent, oral care agent
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
4-chloro-5-methyl-2-propan-2-ylphenol
InChIKey
KFZXVMNBUMVKLN-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not specifically restricted by FDA; permitted under general cosmetic ingredient provisions; no specific monograph
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Chlorothymol.
Calculate MoS for your specific formulation with the MoS Calculator.
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
BRIN Brazil/India Cosmetics
Brazil: Permitted Preservative · max 0,1%
Additional Jurisdictional Restrictions (1)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| BR | permitted_preservative | 0.1 | Not in children's products |
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Biocide
Deodorizer
Pharmaceutical
Preservative
Expert Verdict
Expert safety assessment and concern-level summary for Chlorothymol.
Regulatory Flags
preservative
endocrine_disruptor
Known Synonyms
4-Chloro-2-isopropyl-5-methylphenol
4-06-00-03344
BRN 2084453
Caswell No. 216
4-Chloro-6-isopropyl-3-methylphenol
4-Chlorothymol
Chlorthymol
EINECS 201-930-1
EPA Pesticide Chemical Code 080403
NSC 406261
4-Chlor-2-isopropyl-5-methylphenol
UNII-LJ25TI0CVT
Phenol, 4-chloro-5-methyl-2-(1-methylethyl)-
Chemical Function
Biocide
Deodorizer
Pharmaceutical
Preservative
Regulatory Lists
active_ingredient; Australia
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
CHLOROTHYMOL
ChEMBL ID
CHEMBL1441646
Max Phase
-1
Frequently Asked Questions
Is Chlorothymol allowed in the EU?
Chlorothymol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Chlorothymol do in cosmetics?
Chlorothymol functions as: Preservative, denaturant, deodorizing agent, oral care agent. It is classified as a cosmetic ingredient in our database. CAS number: 89-68-9.
Is Chlorothymol used outside cosmetics?
Chlorothymol also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Chlorothymol compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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