Cholecalciferol/Yeast Polypeptide

INCI: CHOLECALCIFEROL/YEAST POLYPEPTIDE

CAS Number
Not assigned (complex/mixture)
Function
Skin conditioning agent (vitamin D3 complexed with yeast-derived polypeptide)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No specific FDA restriction; no CIR review

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Yeast allergenicity concern; biologically active vitamin D3 component; no dedicated SCCS or CIR assessment; microbial purity of yeast-derived material must be verified

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Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Cholecalciferol/Yeast Polypeptide safe in cosmetics?

Yeast allergenicity concern; biologically active vitamin D3 component; no dedicated SCCS or CIR assessment; microbial purity of yeast-derived material must be verified The EU classifies Cholecalciferol/Yeast Polypeptide as "permitted". Safety rating: MODERATE.

Is Cholecalciferol/Yeast Polypeptide allowed in the EU?

Cholecalciferol/Yeast Polypeptide EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Cholecalciferol/Yeast Polypeptide do in cosmetics?

Cholecalciferol/Yeast Polypeptide functions as: Skin conditioning agent (vitamin D3 complexed with yeast-derived polypeptide). It is classified as a cosmetic ingredient in our database. CAS number: Not assigned (complex/mixture).

What is the Margin of Safety for Cholecalciferol/Yeast Polypeptide?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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