Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
5 study endpoints found for CI 11680 (Pigment Yellow 1). NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 1000 mg/kg bw/day | oral | - | oral | REACH |
| NOAEL | 50000 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
Monoazo pigment permitted in EU under Annex IV with restriction to non-mucous membrane products. Not approved for US cosmetics use. Limited systemic safety data but generally considered low-risk in surface-application cosmetics. Aromatic amine cleavage potential warrants monitoring.
Regulatory Flags
Frequently Asked Questions
Is CI 11680 (Pigment Yellow 1) safe in cosmetics?
Monoazo pigment permitted in EU under Annex IV with restriction to non-mucous membrane products. Not approved for US cosmetics use. Limited systemic safety data but generally considered low-risk in surface-application cosmetics. Aromatic amine cleavage potential warrants monitoring. The EU classifies CI 11680 (Pigment Yellow 1) as "permitted". Safety rating: MODERATE. 5 toxicological study endpoint(s) are available in our database.
Is CI 11680 (Pigment Yellow 1) allowed in the EU?
CI 11680 (Pigment Yellow 1) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does CI 11680 (Pigment Yellow 1) do in cosmetics?
CI 11680 (Pigment Yellow 1) functions as: Colorant. It is classified as a cosmetic ingredient in our database. CAS number: 2512-29-0.
What is the Margin of Safety for CI 11680 (Pigment Yellow 1)?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for CI 11680 (Pigment Yellow 1)?
The NOAEL (No Observed Adverse Effect Level) for CI 11680 (Pigment Yellow 1) is 1000 mg/kg bw/day based on a oral study via oral route in rat. A total of 5 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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