Also known as: C.I. food Red 3, C.I. Acid Red 14, disodium salt, C.I. 14720, 1-Naphthalenesulfonic acid, 4-hydroxy-3-[2-(4-sulfo-1-naphthalenyl)diazenyl]-, sodium salt (1:2), C.I. Acid Red No. 14 (+15 more)
INCI: CI 14720
CI 14720 (Carmoisine / Azorubine) (CAS 3567-69-9) is a cosmetic cosmetic ingredient functioning as Colorant. Synthetic monoazo red dye (Disodium 4-hydroxy-3-[(4-sulphonatonaphthyl. Reported NOAEL =486 mg/kg bw/day in Mouse (ToxValDB_ECHA_IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 3567-69-9 →
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Margin of Safety, dermal absorption, and sensitization profile summaries for CI 14720 (Carmoisine / Azorubine).
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6 study endpoints found for CI 14720 (Carmoisine / Azorubine). NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =486 mg/kg bw/day | dermal | Mouse | chronic | ToxValDB_ECHA_IUCLID |
| NOAEL | =625 mg/kg bw/day | oral | Rat | chronic | ToxValDB_ECHA_IUCLID |
| NOAEL | =1000 mg/kg bw/day | oral | Mouse | chronic | ToxValDB_ECHA_IUCLID |
| NOAEL | =1200 mg/kg bw/day | oral | Rat | reproduction developmental | ToxValDB_ECHA_IUCLID |
| NOAEL | =1250 mg/kg bw/day | oral | Rat | chronic | ToxValDB_ECHA_IUCLID |
| NOAEL | =1785.7 mg/kg bw/day | oral | Mouse | chronic | ToxValDB_ECHA_IUCLID |
International Agency for Research on Cancer (WHO) monograph evaluation.
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| CN | permitted_colorant | - | All cosmetics (Class 1) |
| ASEAN | permitted_colorant | - | All products |
Expert safety assessment and concern-level summary for CI 14720 (Carmoisine / Azorubine).
Public NOAEL study rows linked to CI 14720 (Carmoisine / Azorubine) by CAS number or substance name.
Same-CAS public records found in pharmaceutical data.
Same-CAS rows from the pharmaceutical spoke database.
CI 14720 (Carmoisine / Azorubine) has a safety rating of "MODERATE" in our database. EU status: permitted. US status: prohibited. 6 toxicological study endpoint(s) are available in our database.
CI 14720 (Carmoisine / Azorubine) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
CI 14720 (Carmoisine / Azorubine) functions as: Colorant. Synthetic monoazo red dye (Disodium 4-hydroxy-3-[(4-sulphonatonaphthyl)azo]naphthalenesulphonate), also known as Azorubine, Carmoisine, Acid Red 14, and food colorant E 122. Water-soluble anionic dye imparting a magenta-red hue. Member of the Southampton Six azo dyes associated with hyperactivity concerns in children when ingested. Used in cosmetics, toothpaste, and oral care products.. It is classified as a cosmetic ingredient in our database. CAS number: 3567-69-9.
The NOAEL (No Observed Adverse Effect Level) for CI 14720 (Carmoisine / Azorubine) is =486 mg/kg bw/day based on a chronic study via dermal route in Mouse. A total of 6 study endpoints are available. Source: ToxValDB_ECHA_IUCLID.
CI 14720 (Carmoisine / Azorubine) also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
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