Is CI 61565 safe in cosmetics?
CI 61565 has a safety rating of "MODERATE" in our database. EU status: restricted. US status: permitted.
Moderate
Cosmetic Ingredient
CI 61565
Also known as: 9,10-Anthracenedione, 1,4-bis[(4-methylphenyl)amino]-, D&C Green 6, Anthcoquinone Cyanine Green Base, 1,4-Bis(p-tolylamine)anthraquinone, BRN 2227927 (+12 more)
CI 61565 (CAS 128-80-3) is a cosmetic cosmetic ingredient functioning as Colorant. EU Regulation 1223/2009 status: restricted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 128-80-3 →
Auto-generated CPSR Part A draft with source citations
Function
Colorant
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
1,4-bis(4-methylanilino)anthracene-9,10-dione
InChIKey
TVRGPOFMYCMNRB-UHFFFAOYSA-N
Regulatory Status
EU EU Status
restricted
US US Status
permitted
US Notes
FDA permanently listed as D&C Green No. 6; permitted for externally applied drugs and cosmetics; also permitted in contact lenses (max 0.03%) and surgical sutures; batch certification required
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for CI 61565.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100 - 1,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
EU CosIng Annex Listing
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Annex II — Prohibited
Ref: 1364
(EC) 2013/344
Annex IV — Permitted Colorants
Product type: Green
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (II - Prohibited)
BRIN Brazil/India Cosmetics
Brazil: Prohibited
India: Prohibited (GNRAS)
India: Permitted Colorant
Additional Jurisdictional Restrictions (1)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| ASEAN | permitted_colorant | - | Not eye area |
Additional Ingredient Properties
2 property records from structured ingredient metadata.
colorant
{"Common_Name": "D&C Green No. 6", "Chemical_Name": "Quinizarine Green SS", "CAS_Number": "128-80-3", "Colorant_Type": "Synthetic Dye", "Approved_Uses": "All cosmetics", "Max_Concentration_%": "No limit", "EU_Status": "Approved", "US_FDA_Status": "Approved 21 CFR 74.206", "Notes": "Anthraquinone dye"}
colorant_formulator
{"ci_number": "61565", "ci_name": "Pigment Green 7", "color_category": "green", "color_hex_code": "#008000", "natural_or_synthetic": "synthetic", "organic_or_inorganic": "organic", "lake_or_dye": "pigment", "fda_approved_use": "general", "eu_approved_cosmetic": "yes", "japan_approved": "yes", "china_approved": "yes", "coverage_opacity": "transparent", "tinting_strength": "high", "lightfastness_rat…
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Dye
Fragrance
Regulatory List Membership (4)
EU Banned in Cosmetics
EU Regulated in Personal Care
IFRA Fragrance Transparency List
EU CosIng Cosmetics Ingredient Database
Expert Verdict
Expert safety assessment and concern-level summary for CI 61565.
Regulatory Flags
not-for-hair-dye
fda-certified
anthraquinone
oil-soluble
possible-sensitizer
eu_banned_cosmetics
ifra_fragrance
eu_cosing_listed
Known Synonyms
9,10-Anthracenedione, 1,4-bis[(4-methylphenyl)amino]-
D&C Green 6
Anthcoquinone Cyanine Green Base
1,4-Bis(p-tolylamine)anthraquinone
BRN 2227927
EINECS 204-909-5
Fat-soluble Anthraquinone Green
Macro-lex Green 5B
Micro-lex Green 5B
Toyo Oriental Oil Blue G
Waxoline Green
Bis-1,4-p-tolylaminoanthrchinon
Zelen rozpoustedlova 3
Zelen sudan 4B
1,4-Di(4'-toluidino)anthraquinone
UNII-4QP5U84YF7
Solvaperm Green GSB
Chemical Function
Dye
Fragrance
Regulatory Lists
Europe; Personal care
banned; Europe; Personal care
IFRA Transparency
Europe; Personal care
Europe; Personal care
pharmaceutical
Personal care
Medical/dental
inert_ingredient; non_food_use; Pesticides
Australian Status
AICIS status: listed
Frequently Asked Questions
Is CI 61565 allowed in the EU?
CI 61565 EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does CI 61565 do in cosmetics?
CI 61565 functions as: Colorant. It is classified as a cosmetic ingredient in our database. CAS number: 128-80-3.
Is CI 61565 used outside cosmetics?
CI 61565 also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check CI 61565 compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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