Is CI 71105 safe in cosmetics?
CI 71105 has a safety rating of "MODERATE" in our database. EU status: restricted. US status: prohibited.
Moderate
Cosmetic Ingredient
CI 71105
Also known as: C.I. Vat Orange 7, C.I. 71105, Bisbenzimidazo[2,1-b:2',1'-i]benzo[lmn][3,8]phenanthroline-8,17-dione, 4-26-00-02613, Bordeaux RRN (+14 more)
CI 71105 (CAS 4424-06-0) is a cosmetic cosmetic ingredient functioning as Colorant. NOAEL 1000 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: restricted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 4424-06-0 →
Auto-generated CPSR Part A draft with source citations
Function
Colorant
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
3,10,17,24-tetrazaoctacyclo[13.13.2.02,10.04,9.012,29.016,24.018,23.026,30]triaconta-1(29),2,4,6,8,12,14,16,18,20,22,26(30),27-tridecaene-11,25-dione
InChIKey
DGBWPZSGHAXYGK-UHFFFAOYSA-N
Regulatory Status
EU EU Status
restricted
US US Status
prohibited
US Notes
Not listed as an FDA-certified or FDA-exempt color additive for cosmetic use in the US; no D&C or FD&C designation found in FDA color additive database; EU-permitted colorant (Annex IV; EINECS 224-597-4); not for use in eye or mucous membrane area
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for CI 71105.
Calculate MoS for your specific formulation with the MoS Calculator.
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for CI 71105 across SCCS product categories, with measured dermal absorption where available.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
EU CosIng Annex Listing
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Annex IV — Permitted Colorants
Product type: Orange
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (IV - Colorants)
Product type: Not to be used in products applied on mucous membranes.
BRIN Brazil/India Cosmetics
India: Permitted Colorant
Additional Jurisdictional Restrictions (1)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| ASEAN | permitted_colorant | - | All products |
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Dye
Pigment
Expert Verdict
Expert safety assessment and concern-level summary for CI 71105.
Regulatory Flags
not-fda-approved
vat-dye
not-for-eye-area
not-for-mucous-membranes
regulatory-verification-needed
Known Synonyms
C.I. Vat Orange 7
C.I. 71105
Bisbenzimidazo[2,1-b:2',1'-i]benzo[lmn][3,8]phenanthroline-8,17-dione
4-26-00-02613
Bordeaux RRN
Brilliant Orange GR
BRN 0061891
Cibanone Brilliant Orange GR
EINECS 224-597-4
Fenanthren Brilliant Orange GR
Hostaperm Orange GR
Hostaperm Vat Orange GR
Hostavat Brilliant Orange GR
Indanthren Brilliant Orange GR
Indanthrene Brilliant Orange GR
Indanthrene Brilliant Orange GRP
IndoFast Orange OV 5983
Mikethren Brilliant Orange GR
Mikethrene Orange GR
Chemical Function
Dye
Pigment
Regulatory Lists
Arts and crafts/Office supplies - body paint - tattoo ink; Europe
Arts and crafts/Office supplies - body paint - tattoo ink; Europe
Australian Status
AICIS status: listed
Frequently Asked Questions
Is CI 71105 allowed in the EU?
CI 71105 EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does CI 71105 do in cosmetics?
CI 71105 functions as: Colorant. It is classified as a cosmetic ingredient in our database. CAS number: 4424-06-0.
Is CI 71105 used outside cosmetics?
CI 71105 also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check CI 71105 compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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