Is Cinnamyl Acetate safe in cosmetics?
Cinnamyl Acetate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Cinnamyl Acetate
Also known as: 2-Propen-1-ol, 3-phenyl-, acetate, 1-Acetoxy-3-phenyl-2-propene, BRN 2046000, NSC 46109, 1-phenyl-3-acetoxyprop-1-ene (+7 more)
INCI: CINNAMYL ACETATE
Cinnamyl Acetate (CAS 103-54-8) is a cosmetic cosmetic ingredient functioning as Fragrance ingredient with balsamic, sweet, floral-cinnamon odor. NOAEL 275 mg/kg bw/day (PDF-verified against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and food safety data.
View industrial chemical safety profile for CAS 103-54-8 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance ingredient with balsamic, sweet, floral-cinnamon odor
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
[(E)-3-phenylprop-2-enyl] acetate
InChIKey
WJSDHUCWMSHDCR-VMPITWQZSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted; FEMA GRAS. RIFM safety assessment supports use. Extensive RIFM data available.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Cinnamyl Acetate.
Calculate MoS for your specific formulation with the MoS Calculator.
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for Cinnamyl Acetate across SCCS product categories, with measured dermal absorption where available.
HRIPT Human Patch Test Studies
2 human repeat insult patch tests aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HRIPT | 101 | 0 | 3424 | 3424 | non-sensitizer |
| HMT | - | 0 | 3240 | - | - |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100 - 1,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (3)
JECFA Number
650
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
3-PHENYLALLYL ACETATE | 2000 | No safety concern at current levels of intake when used as a flavouring agent | TRS 901-JECFA 55/22 | FAS 46-JECFA 55/79
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
CINNAMYL ACETATE | 2000 | No safety concern at current levels of intake when used as a flavouring agent | TRS 901-JECFA 55/22 | FAS 46-JECFA 55/79
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (2)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for Cinnamyl Acetate.
Regulatory Flags
potential-allergen
fragrance-component
ifra_fragrance
fda_food_additive
jecfa_safe
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Cinnamyl Acetate by CAS number or substance name.
Studies
3
Lowest NOAEL
200 mg/kg bw/day
Highest NOAEL
200 mg/kg bw/day
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip
Known Synonyms
2-Propen-1-ol, 3-phenyl-, acetate
1-Acetoxy-3-phenyl-2-propene
BRN 2046000
NSC 46109
1-phenyl-3-acetoxyprop-1-ene
3-Phenyl-2-propenyl acetate
3-phenyl-2-propen-1-ol acetate
3-phenyl-2-propen-1-yl acetate
3-phenylallyl acetate
PhCH=CHCH2OAc
acetic acid cinnamyl ester
gamma-phenylallyl acetate
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
Australia; Food and drug - smoking-related products
IFRA Transparency
Europe
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
detected; Europe; Personal care - sexual wellness
detected; Europe; Personal care - sexual wellness
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in food safety data.
SOURCE
EFSA / FDA GRAS
food_additives
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
CINNAMYL ACETATE
ADI
No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
Food Category
flavoring
Frequently Asked Questions
Is Cinnamyl Acetate allowed in the EU?
Cinnamyl Acetate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Cinnamyl Acetate do in cosmetics?
Cinnamyl Acetate functions as: Fragrance ingredient with balsamic, sweet, floral-cinnamon odor. It is classified as a cosmetic ingredient in our database. CAS number: 103-54-8.
Is Cinnamyl Acetate used outside cosmetics?
Cinnamyl Acetate also appears in industrial chemical safety and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Cinnamyl Acetate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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