Acetanilid

INCI: ACETANILID

CAS Number
103-84-4
Function
Historical antipyretic/analgesic; no legitimate cosmetic function
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status prohibited
US Notes Not permitted in cosmetics by practice; FDA would consider it an unsafe additive

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
high
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Methemoglobinemia risk โ€” metabolizes to aniline (a known toxic/carcinogenic aromatic amine). Absolute ban in EU cosmetics. Do not formulate under any circumstances.

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Concern Level: High

Regulatory Flags

ifra_fragrance

Frequently Asked Questions

Is Acetanilid safe in cosmetics?

Methemoglobinemia risk โ€” metabolizes to aniline (a known toxic/carcinogenic aromatic amine). Absolute ban in EU cosmetics. Do not formulate under any circumstances. The EU classifies Acetanilid as "prohibited". Safety rating: POOR.

Is Acetanilid allowed in the EU?

Acetanilid EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Acetanilid do in cosmetics?

Acetanilid functions as: Historical antipyretic/analgesic; no legitimate cosmetic function. It is classified as a cosmetic ingredient in our database. CAS number: 103-84-4.

What is the Margin of Safety for Acetanilid?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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