Is Cinnamyl Isobutyrate safe in cosmetics?
Cinnamyl Isobutyrate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Cinnamyl Isobutyrate
Also known as: BRN 3130772, Cinnamyl 2-methylpropanoate, EINECS 203-126-6, FEMA No. 2297, 2-Methyl-propanoic acid, 3-phenyl-2-propenyl ester (+4 more)
INCI: CINNAMYL ISOBUTYRATE
Cinnamyl Isobutyrate (CAS 103-59-3) is a cosmetic cosmetic ingredient functioning as Fragrance ingredient with sweet, fruity, balsamic odor. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and food safety data.
View industrial chemical safety profile for CAS 103-59-3 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance ingredient with sweet, fruity, balsamic odor
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
[(E)-3-phenylprop-2-enyl] 2-methylpropanoate
InChIKey
KLKQSZIWHVEARN-RMKNXTFCSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted; FEMA GRAS for flavor use. RIFM member of the cinnamyl ester group. No specific CIR review.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Cinnamyl Isobutyrate.
Calculate MoS for your specific formulation with the MoS Calculator.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 2700 | - | - |
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (2)
JECFA Number
653
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
CINNAMYL ISOBUTYRATE | 2000 | No safety concern at current levels of intake when used as a flavouring agent | TRS 901-JECFA 55/22 | FAS 46-JECFA 55/79
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (3)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for Cinnamyl Isobutyrate.
Regulatory Flags
potential-allergen
fragrance-component
ifra_fragrance
fda_food_additive
jecfa_safe
Known Synonyms
BRN 3130772
Cinnamyl 2-methylpropanoate
EINECS 203-126-6
FEMA No. 2297
2-Methyl-propanoic acid, 3-phenyl-2-propenyl ester
NSC 46133
3-Phenyl-2-propen-1-yl isobutyrate
3-Phenyl-2-propen-1-yl 2-methylpropanoate
UNII-C286CMK03D
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
IFRA Transparency
Europe
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
consumer_product
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in food safety data.
SOURCE
EFSA / FDA GRAS
food_additives
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
CINNAMYL ISOBUTYRATE
ADI
No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
Food Category
flavoring
Frequently Asked Questions
Is Cinnamyl Isobutyrate allowed in the EU?
Cinnamyl Isobutyrate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Cinnamyl Isobutyrate do in cosmetics?
Cinnamyl Isobutyrate functions as: Fragrance ingredient with sweet, fruity, balsamic odor. It is classified as a cosmetic ingredient in our database. CAS number: 103-59-3.
Is Cinnamyl Isobutyrate used outside cosmetics?
Cinnamyl Isobutyrate also appears in industrial chemical safety and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Cinnamyl Isobutyrate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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