cis-3-Hexenal

INCI: cis-3-HEXENAL

CAS Number
6789-80-6
Function
Fragrance with intense green, freshly cut grass note
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes FEMA GRAS; RIFM safety assessment published 2024; no FDA cosmetic restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
high
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Aldehyde with structural alert for skin sensitization via Schiff base mechanism; highly volatile and reactive; requires strict concentration control in leave-on products

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Concern Level: Moderate

Regulatory Flags

potential-allergen fragrance-component ifra_fragrance fda_food_additive jecfa_safe

Frequently Asked Questions

Is cis-3-Hexenal safe in cosmetics?

Aldehyde with structural alert for skin sensitization via Schiff base mechanism; highly volatile and reactive; requires strict concentration control in leave-on products The EU classifies cis-3-Hexenal as "permitted". Safety rating: MODERATE.

Is cis-3-Hexenal allowed in the EU?

cis-3-Hexenal EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does cis-3-Hexenal do in cosmetics?

cis-3-Hexenal functions as: Fragrance with intense green, freshly cut grass note. It is classified as a cosmetic ingredient in our database. CAS number: 6789-80-6.

What is the Margin of Safety for cis-3-Hexenal?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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