Good Surfactant

Cocamidopropyl Hydroxysultaine

INCI: COCAMIDOPROPYL HYDROXYSULTAINE

CAS Number
68139-30-0
Function
Surfactant; co-surfactant; foam stabilizer; viscosity builder
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
EU Max Conc. No concentration cap; used at 2โ€“8% as co-surfactant
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Next-generation amphoteric positioned as CAPB replacement for sensitive skin formulations. Colonial Chemical Zein test data shows synergistic irritation reduction when combined with anionic surfactants โ€” overall irritation lower than predicted weighted average of individual components. No DMAPA or amidoamine impurity concerns.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Preferred amphoteric co-surfactant for sensitive skin, baby, and clean-beauty formulations. Sultaine chemistry eliminates the DMAPA/amidoamine sensitization concern that made CAPB Allergen of the Year 2004. Colonial Chemical data demonstrates synergistic irritation reduction when blended with anionic surfactants. Excellent foam stability and viscosity building with superior safety profile compared to CAPB.

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Concern Level: Low

Regulatory Flags

amphoteric sultaine no-sensitization-risk mild synergistic-mildness baby-safe epa_safer_alternative

Frequently Asked Questions

Is Cocamidopropyl Hydroxysultaine safe in cosmetics?

Preferred amphoteric co-surfactant for sensitive skin, baby, and clean-beauty formulations. Sultaine chemistry eliminates the DMAPA/amidoamine sensitization concern that made CAPB Allergen of the Year 2004. Colonial Chemical data demonstrates synergistic irritation reduction when blended with anionic surfactants. Excellent foam stability and viscosity building with superior safety profile compared to CAPB. The EU classifies Cocamidopropyl Hydroxysultaine as "permitted". Safety rating: GOOD.

Is Cocamidopropyl Hydroxysultaine allowed in the EU?

Cocamidopropyl Hydroxysultaine EU regulatory status: permitted. Maximum allowed concentration: No concentration cap; used at 2โ€“8% as co-surfactant. This is based on EU Regulation 1223/2009 and its amendments.

What does Cocamidopropyl Hydroxysultaine do in cosmetics?

Cocamidopropyl Hydroxysultaine functions as: Surfactant; co-surfactant; foam stabilizer; viscosity builder. It is classified as a Surfactant in our database. CAS number: 68139-30-0.

What is the Margin of Safety for Cocamidopropyl Hydroxysultaine?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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