Distearoylethyl Dimonium Chloride
INCI: DISTEAROYLETHYL DIMONIUM CHLORIDE
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
3 study endpoints found for Distearoylethyl Dimonium Chloride. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | >500 mg/kg bw/day | oral | rat | oral | REACH |
| NOEL | 1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >500 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
Extremely safe esterquat with low systemic toxicity, minimal dermal absorption (0.2%), no sensitization, and no genotoxicity concerns.
Regulatory Flags
Frequently Asked Questions
Is Distearoylethyl Dimonium Chloride safe in cosmetics?
Extremely safe esterquat with low systemic toxicity, minimal dermal absorption (0.2%), no sensitization, and no genotoxicity concerns. The EU classifies Distearoylethyl Dimonium Chloride as "permitted". Safety rating: EXCELLENT. 3 toxicological study endpoint(s) are available in our database.
Is Distearoylethyl Dimonium Chloride allowed in the EU?
Distearoylethyl Dimonium Chloride EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Distearoylethyl Dimonium Chloride do in cosmetics?
Distearoylethyl Dimonium Chloride functions as: Antistatic Agent, Hair Conditioning Agent. It is classified as a Surfactant in our database. CAS number: 67846-68-8.
What is the Margin of Safety for Distearoylethyl Dimonium Chloride?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Distearoylethyl Dimonium Chloride?
The NOAEL (No Observed Adverse Effect Level) for Distearoylethyl Dimonium Chloride is >500 mg/kg bw/day based on a oral study via oral route in rat. A total of 3 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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