Excellent Surfactant NOAEL Data

Lauroyl Lysine

INCI: LAUROYL LYSINE

CAS Number
52315-75-0
Function
Hair Conditioning, Skin Conditioning, Viscosity Controlling, Pigment Dispersant
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes CIR 2017: safe when formulated to be non-irritating. Max use 45% in lipsticks.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for Lauroyl Lysine. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOEL >1000 mg/kg bw/day oral rat oral REACH

Expert Verdict

CIR 2017: amino acid alkyl amides safe as used. Non-irritating at 20%. Metabolites are L-lysine and lauric acid (dietary constituents). Water and oil insoluble. COSMOS/ECOCERT eligible.

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Concern Level: None

Frequently Asked Questions

Is Lauroyl Lysine safe in cosmetics?

CIR 2017: amino acid alkyl amides safe as used. Non-irritating at 20%. Metabolites are L-lysine and lauric acid (dietary constituents). Water and oil insoluble. COSMOS/ECOCERT eligible. The EU classifies Lauroyl Lysine as "permitted". Safety rating: EXCELLENT. 1 toxicological study endpoint(s) are available in our database.

Is Lauroyl Lysine allowed in the EU?

Lauroyl Lysine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Lauroyl Lysine do in cosmetics?

Lauroyl Lysine functions as: Hair Conditioning, Skin Conditioning, Viscosity Controlling, Pigment Dispersant. It is classified as a Surfactant in our database. CAS number: 52315-75-0.

What is the Margin of Safety for Lauroyl Lysine?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Lauroyl Lysine?

The NOAEL (No Observed Adverse Effect Level) for Lauroyl Lysine is >1000 mg/kg bw/day based on a oral study via oral route in rat. Source: REACH.

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