Excellent Cosmetic Ingredient NOAEL Data

Cocos Nucifera Fruit Juice

INCI: COCOS NUCIFERA FRUIT JUICE

CAS Number
8001-31-8
Function
Skin conditioning / humectant
Safety Rating
EXCELLENT

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes FDA permitted for cosmetic use; no specific restrictions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

10 study endpoints found for Cocos Nucifera Fruit Juice. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 4850 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
NOAEL 20000 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
NOAEL 1817 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 1777 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 1772 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 1780 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 10000 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
NOAEL 4000 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 7000 mg/kg bw/day oral gerbil Short Term Toxicity COSMOS_DB
NOAEL 22500 mg/kg bw/day oral mouse Special Toxicology Study COSMOS_DB

Expert Verdict

Cocos Nucifera Fruit Juice is a permitted humectant and skin conditioning agent with excellent safety profile, low absorption, and minimal sensitization risk.

⚠️
Concern Level: None

Regulatory Flags

epa_safer_alternative ifra_fragrance fda_food_additive

Frequently Asked Questions

Is Cocos Nucifera Fruit Juice safe in cosmetics?

Cocos Nucifera Fruit Juice is a permitted humectant and skin conditioning agent with excellent safety profile, low absorption, and minimal sensitization risk. The EU classifies Cocos Nucifera Fruit Juice as "permitted". Safety rating: EXCELLENT. 10 toxicological study endpoint(s) are available in our database.

Is Cocos Nucifera Fruit Juice allowed in the EU?

Cocos Nucifera Fruit Juice EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Cocos Nucifera Fruit Juice do in cosmetics?

Cocos Nucifera Fruit Juice functions as: Skin conditioning / humectant. It is classified as a cosmetic ingredient in our database. CAS number: 8001-31-8.

What is the Margin of Safety for Cocos Nucifera Fruit Juice?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Cocos Nucifera Fruit Juice?

The NOAEL (No Observed Adverse Effect Level) for Cocos Nucifera Fruit Juice is 4850 mg/kg bw/day based on a Short Term Toxicity study via oral route in rat. A total of 10 study endpoints are available. Source: COSMOS_DB.

Compliance Tools

Check Cocos Nucifera Fruit Juice compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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