Excellent Cosmetic Ingredient NOAEL Data

Cocos Nucifera Water

INCI: COCOS NUCIFERA WATER

CAS Number
8001-31-8
Function
Fragrance ingredient; Skin-conditioning agent – humectant; Hair conditioning agent
Safety Rating
EXCELLENT

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes No FDA restrictions; CIR Panel: safe in present practices of use and concentration

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

10 study endpoints found for Cocos Nucifera Water. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 4850 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
NOAEL 20000 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
NOAEL 1817 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 1777 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 1772 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 1780 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 10000 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
NOAEL 4000 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 7000 mg/kg bw/day oral gerbil Short Term Toxicity COSMOS_DB
NOAEL 22500 mg/kg bw/day oral mouse Special Toxicology Study COSMOS_DB

Expert Verdict

Natural ingredient containing phytohormones; showed weak estrogen-like activity only at oral doses far exceeding cosmetic exposure. DART studies showed no reproductive effects at cosmetic-relevant levels. Inhalation at typical spray use concentrations not a concern.

⚠️
Concern Level: Low

Regulatory Flags

fragrance-component natural-origin epa_safer_alternative ifra_fragrance fda_food_additive

Frequently Asked Questions

Is Cocos Nucifera Water safe in cosmetics?

Natural ingredient containing phytohormones; showed weak estrogen-like activity only at oral doses far exceeding cosmetic exposure. DART studies showed no reproductive effects at cosmetic-relevant levels. Inhalation at typical spray use concentrations not a concern. The EU classifies Cocos Nucifera Water as "permitted". Safety rating: EXCELLENT. 10 toxicological study endpoint(s) are available in our database.

Is Cocos Nucifera Water allowed in the EU?

Cocos Nucifera Water EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Cocos Nucifera Water do in cosmetics?

Cocos Nucifera Water functions as: Fragrance ingredient; Skin-conditioning agent – humectant; Hair conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: 8001-31-8.

What is the Margin of Safety for Cocos Nucifera Water?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Cocos Nucifera Water?

The NOAEL (No Observed Adverse Effect Level) for Cocos Nucifera Water is 4850 mg/kg bw/day based on a Short Term Toxicity study via oral route in rat. A total of 10 study endpoints are available. Source: COSMOS_DB.

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