Regulatory Status
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Safety Data
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Expert Verdict
Contains berberine (isoquinoline alkaloid), which at high concentrations can be cytotoxic; limited published cosmetic safety data specific to this INCI; formulators should verify alkaloid concentration. Derived from Coptis japonica (Japanese Goldthread); berberine content provides natural antimicrobial and anti-inflammatory activity; widely used in East Asian traditional medicine
Regulatory Flags
Frequently Asked Questions
Is Coptis Japonica Extract safe in cosmetics?
Contains berberine (isoquinoline alkaloid), which at high concentrations can be cytotoxic; limited published cosmetic safety data specific to this INCI; formulators should verify alkaloid concentration. Derived from Coptis japonica (Japanese Goldthread); berberine content provides natural antimicrobial and anti-inflammatory activity; widely used in East Asian traditional medicine The EU classifies Coptis Japonica Extract as "permitted". Safety rating: MODERATE.
Is Coptis Japonica Extract allowed in the EU?
Coptis Japonica Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Coptis Japonica Extract do in cosmetics?
Coptis Japonica Extract functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 223748-66-1.
What is the Margin of Safety for Coptis Japonica Extract?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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