Is CURRY RED safe in cosmetics?
CURRY RED has a safety rating of "MODERATE" in our database. EU status: restricted. 10 toxicological study endpoint(s) are available in our database.
CURRY RED
Also known as: 2-Naphthalenesulfonic acid, 6-hydroxy-5-[(2-methoxy-5-methyl-4-sulfophenyl)azo]-, disodium salt, FD&C Red no.40, C.I. Food Red 17, C. I. 16035, Allura Red AC Dye (+7 more)
CURRY RED (CAS 25956-17-6) is a cosmetic cosmetic ingredient functioning as Hair Dyeing. NOAEL 7300 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: restricted, max III/191 (Curry Red) IV/32 (CI 16035). Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 25956-17-6 →
Auto-generated CPSR Part A draft with source citations
Function
Hair Dyeing
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
disodium;6-hydroxy-5-[(2-methoxy-5-methyl-4-sulfonatophenyl)diazenyl]naphthalene-2-sulfonate
InChIKey
CEZCCHQBSQPRMU-UHFFFAOYSA-L
Regulatory Status
EU EU Status
restricted
EU Max Conc.
III/191 (Curry Red)
IV/32 (CI 16035)
US US Status
Not specifically regulated
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Toxicological Studies
10 study endpoints found for CURRY RED. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 125 mg/kg bw/day | oral | dog | Subchronic | COSMOS_DB |
| NOAEL | 200 mg/kg bw/day | oral | rat | Developmental | COSMOS_DB |
| NOAEL | 250 mg/kg bw/day | oral | dog | Short Term Toxicity | COSMOS_DB |
| NOAEL | 700 mg/kg bw/day | oral | rabbit | Developmental | COSMOS_DB |
| NOAEL | 939.3 mg/kg bw/day | oral | rat | Reproductive-developmental | COSMOS_DB |
| NOAEL | 1500 mg/kg bw/day | oral | swine | Short Term Toxicity | COSMOS_DB |
| NOAEL | =10 mg/kg bw/day | oral: feed | Mouse | reproduction toxicity | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| NOAEL | =10 mg/kg bw/day | oral: feed | Mouse | reproduction toxicity | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| NOAEL | =7 mg/kg bw/day | oral | - | carcinogenicity | SCCNFP_vision_codex |
| NOAEL | =7 mg/kg bw/day | oral | - | carcinogenicity | SCCNFP_vision_codex |
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for CURRY RED across SCCS product categories, with measured dermal absorption where available.
EPA ToxValDB — Toxicity Values
10 toxicity values from EPA ToxValDB (aggregated from CCTE, HPV, ToxRefDB, IRIS, and other regulatory dossiers).
| Endpoint | Value | Species | Route | Duration | Source |
|---|---|---|---|---|---|
| NOAEL | =901 mg/kg-day | Rat | oral | chronic | ECHA IUCLID |
| NOAEL | =2829 mg/kg-day | Rat | oral | chronic | ECHA IUCLID |
| LD50 | >10000 mg/kg | Rabbit | dermal | - | ECHA IUCLID |
| LD50 | >10000 mg/kg | Rabbit | dermal | - | ECHA IUCLID |
| NOAEL | =260.2 mg/kg-day | Rat | oral | - | ECHA IUCLID |
| NOAEL | =260.2 mg/kg-day | Rat | oral | - | ECHA IUCLID |
| NOAEL | =200 mg/kg-day | Rat | oral | - | ECHA IUCLID |
| NOAEL | =200 mg/kg-day | Rat | oral | - | ECHA IUCLID |
| NOAEL | =260.2 mg/kg-day | Rat | oral | short-term | ECHA IUCLID |
| NOAEL | =200 mg/kg-day | Rat | oral | - | ECHA IUCLID |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
EU CosIng Annex Listing
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Annex IV — Permitted Colorants
Product type: Red
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (III - Restricted)
Product type: Hair dye substance in non-oxidative hair dye products. Max: 0.004.
BRIN Brazil/India Cosmetics
India: Restricted · max 0.004
India: Permitted Colorant
Additional Jurisdictional Restrictions (4)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| CN | permitted_colorant | - | All cosmetics (Class 1) |
| BR | permitted_colorant | - | Column 2: All products except eye area |
| ASEAN | restricted | 0.4% | Non-oxidative hair dye products only |
| ASEAN | permitted_colorant | - | All products (non-oxidative hair dye limit 0.4% Annex III) |
Additional Ingredient Properties
1 property record from structured ingredient metadata.
hair_dye
{"cas_number": "25956-17-6", "ingredient_class": "direct_dye", "chemical_class": "azo", "color_result_on_hair": "Red", "shade_range": "red", "primary_function": "direct_deposit", "requires_developer": "no", "deposit_only": "yes", "permanence": "semi_permanent", "wash_fastness_shampoos": "4-8", "light_fastness": "good", "oxidation_mechanism": "direct_absorption", "hair_penetration_depth": "surface_…
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Dye
Flavouring and nutrient
Fragrance
Regulatory List Membership (5)
EU Restricted for Children (Cosmetics)
IFRA Fragrance Transparency List
EPA Safer Chemical Ingredients List (SCIL)
FDA Substances Added to Food (EAFUS)
EU CosIng Cosmetics Ingredient Database
Expert Verdict
Expert safety assessment and concern-level summary for CURRY RED.
Regulatory Flags
cosing-sourced
eu-restricted
needs-enrichment
eu_children_restricted
epa_safer_alternative
ifra_fragrance
fda_food_additive
eu_cosing_listed
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to CURRY RED by CAS number or substance name.
Studies
38
Lowest NOAEL
7
Highest NOAEL
3750
Units vary across source rows: mg/kg bw/day, mg/kg
COSMOS_DB
ToxValDB_ECHA_IUCLID
EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx
SCCNFP_vision_codex
Known Synonyms
2-Naphthalenesulfonic acid, 6-hydroxy-5-[(2-methoxy-5-methyl-4-sulfophenyl)azo]-, disodium salt
FD&C Red no.40
C.I. Food Red 17
C. I. 16035
Allura Red AC Dye
Disodium 6-hydroxy-5-((2-methoxy-5-methyl-4-sulfophenyl)azo)-2-naphthalenesulfonate
Disodium 6-hydroxy-5-((6-methoxy-4-sulfo-m-tolyl)azo)-2-naphthalenesulfonate
EINECS 247-368-0
UNII-WZB9127XOA
Fancy Red
Japan Food Red No. 40
Japan Red 40
Chemical Function
Dye
Regulatory Lists
Europe; Personal care - hair coloring
IFRA Transparency
inert_ingredient; non_food_use; Pesticides
Arts and crafts/Office supplies - body paint - tattoo ink; Europe
children; Europe; Personal care
children; Europe; Personal care - specialized bath products - bath salts
children; Europe; Personal care - body hygiene - body wash
children; Europe; Personal care - hair styling and care - shampoo
children; Europe; Personal care - specialized bath products - bubble bath
children; Europe; Personal care
children; Europe; Personal care
children; Europe; Personal care
Europe; Personal care - hair coloring
Europe; Personal care - hair coloring
Europe; Personal care - hair coloring
Europe; Personal care; restricted
SCIL (9/2019)
inert_ingredient; Pesticides
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3188816
Frequently Asked Questions
Is CURRY RED allowed in the EU?
CURRY RED EU regulatory status: restricted. Maximum allowed concentration: III/191 (Curry Red) IV/32 (CI 16035). This is based on EU Regulation 1223/2009 and its amendments.
What does CURRY RED do in cosmetics?
CURRY RED functions as: Hair Dyeing. It is classified as a cosmetic ingredient in our database. CAS number: 25956-17-6.
What is the NOAEL for CURRY RED?
The NOAEL (No Observed Adverse Effect Level) for CURRY RED is 125 mg/kg bw/day based on a Subchronic study via oral route in dog. A total of 10 study endpoints are available. Source: COSMOS_DB.
Is CURRY RED used outside cosmetics?
CURRY RED also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check CURRY RED compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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Chemical family
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Chemical family
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Chemical family
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