Cutibacterium Acnes Bacteriophages

INCI: CUTIBACTERIUM ACNES BACTERIOPHAGES

CAS Number
Not assigned (biological entity - viral particles)
Function
Skin Conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not specifically prohibited; novel ingredient category without dedicated monograph

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Shown to be non-irritant to human skin and ocular tissues in ex vivo models; does not permeate through human epidermis; well-tolerated in randomized, vehicle-controlled clinical studies. Phages that specifically target C. acnes without harming beneficial bacteria; the BX001 three-phage cocktail demonstrated statistically significant reduction in facial C. acnes counts in a dose-dependent manner; effective against antibiotic-resistant strains and biofilm-embedded bacteria

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Concern Level: Moderate

Frequently Asked Questions

Is Cutibacterium Acnes Bacteriophages safe in cosmetics?

Shown to be non-irritant to human skin and ocular tissues in ex vivo models; does not permeate through human epidermis; well-tolerated in randomized, vehicle-controlled clinical studies. Phages that specifically target C. acnes without harming beneficial bacteria; the BX001 three-phage cocktail demonstrated statistically significant reduction in facial C. acnes counts in a dose-dependent manner; effective against antibiotic-resistant strains and biofilm-embedded bacteria The EU classifies Cutibacterium Acnes Bacteriophages as "permitted". Safety rating: MODERATE.

Is Cutibacterium Acnes Bacteriophages allowed in the EU?

Cutibacterium Acnes Bacteriophages EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Cutibacterium Acnes Bacteriophages do in cosmetics?

Cutibacterium Acnes Bacteriophages functions as: Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned (biological entity - viral particles).

What is the Margin of Safety for Cutibacterium Acnes Bacteriophages?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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