Moderate Cosmetic Ingredient NOAEL Data SCCS/CIR Reviewed

Cyamopsis Tetragonoloba Gum

INCI: CYAMOPSIS TETRAGONOLOBA GUM

CAS Number
9000-30-0
Function
Binding; Emulsion Stabilising; Film Forming; Viscosity Controlling
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes GRAS (Generally Recognized As Safe); allowed in both food and cosmetic applications

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

10 study endpoints found for Cyamopsis Tetragonoloba Gum. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 2500 mg/kg bw/day oral rat Special Toxicology Study COSMOS_DB
NOAEL 2500 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 700 mg/kg bw/day oral rabbit Developmental COSMOS_DB
NOAEL 500 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 200 mg/kg bw/day oral monkey Subchronic COSMOS_DB
NOAEL 800 mg/kg bw/day oral mouse Developmental COSMOS_DB
NOAEL 900 mg/kg bw/day oral rat Developmental COSMOS_DB
NOAEL 600 mg/kg bw/day oral hamster Developmental COSMOS_DB
NOAEL 10000 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 15000 mg/kg bw/day oral mouse Subchronic COSMOS_DB

Safety Opinions

Official safety assessments from the Scientific Committee on Consumer Safety (SCCS) and Cosmetic Ingredient Review (CIR).

cir
Verdict: safe
NOAEL: 1000 mg/kg body weight (oral)

netration of these ingredients would be unlikely. The Panel concluded that these galactomannans are safe in the present practices of use and concentration described in this safety assessment. Keywords galactomannans, safety, cosmetics Introduction As given in the International Cosmetic Ingredient Dictio

cir
Verdict: safe
NOAEL: 1000 mg/kg body weight (not specified)

netration of these ingredients would be unlikely. The Panel concluded that these galactomannans are safe in the present practices of use and concentration described in this safety assessment. Keywords galactomannans, safety, cosmetics Introduction As given in the International Cosmetic Ingredient Dictio

Expert Verdict

Generally safe and non-toxic; recommended at concentrations โ‰ค2% to avoid overly viscous formulations; well-tolerated by sensitive skin; biodegradable. Commonly known as Guar Gum; derived from the ground endosperm of guar seeds (Cyamopsis tetragonoloba); forms a high-viscosity gel in water; vegan and halal compatible; pH range 5-7; alternatives include xanthan gum, carrageenan, and hydroxyethylcellulose

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Concern Level: High

Regulatory Flags

epa_safer_alternative fda_food_additive

Frequently Asked Questions

Is Cyamopsis Tetragonoloba Gum safe in cosmetics?

Generally safe and non-toxic; recommended at concentrations โ‰ค2% to avoid overly viscous formulations; well-tolerated by sensitive skin; biodegradable. Commonly known as Guar Gum; derived from the ground endosperm of guar seeds (Cyamopsis tetragonoloba); forms a high-viscosity gel in water; vegan and halal compatible; pH range 5-7; alternatives include xanthan gum, carrageenan, and hydroxyethylcellulose The EU classifies Cyamopsis Tetragonoloba Gum as "permitted". Safety rating: MODERATE. 10 toxicological study endpoint(s) are available in our database. This ingredient has been reviewed by cir.

Is Cyamopsis Tetragonoloba Gum allowed in the EU?

Cyamopsis Tetragonoloba Gum EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Cyamopsis Tetragonoloba Gum do in cosmetics?

Cyamopsis Tetragonoloba Gum functions as: Binding; Emulsion Stabilising; Film Forming; Viscosity Controlling. It is classified as a cosmetic ingredient in our database. CAS number: 9000-30-0.

What is the Margin of Safety for Cyamopsis Tetragonoloba Gum?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Cyamopsis Tetragonoloba Gum?

The NOAEL (No Observed Adverse Effect Level) for Cyamopsis Tetragonoloba Gum is 2500 mg/kg bw/day based on a Special Toxicology Study study via oral route in rat. A total of 10 study endpoints are available. Source: COSMOS_DB.

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