Cyclododecyl Formate

INCI: CYCLODODECYL FORMATE

CAS Number
59052-82-3
Function
Fragrance / perfuming agent
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status restricted
🇺🇸 US Status permitted
US Notes Allowed - not prohibited or restricted; classified as a fragrance ingredient.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

RIFM safety assessment found it is not expected to be genotoxic, not a skin sensitizer, and not photoirritating/photoallergenic (no UV absorption between 290-450 nm). Classified as Skin Irrit. 2 (H315) and Eye Irrit. 2A (H319) under GHS.. Molecular formula C₁₃H₂₄O₂ (MW 212.33 g/mol); musk-type fragrance note; hydrolytically cleaved to cyclododecanol and formic acid.

⚠️
Concern Level: High

Regulatory Flags

potential-allergen fragrance-component ifra_fragrance

Frequently Asked Questions

Is Cyclododecyl Formate safe in cosmetics?

RIFM safety assessment found it is not expected to be genotoxic, not a skin sensitizer, and not photoirritating/photoallergenic (no UV absorption between 290-450 nm). Classified as Skin Irrit. 2 (H315) and Eye Irrit. 2A (H319) under GHS.. Molecular formula C₁₃H₂₄O₂ (MW 212.33 g/mol); musk-type fragrance note; hydrolytically cleaved to cyclododecanol and formic acid. The EU classifies Cyclododecyl Formate as "restricted". Safety rating: MODERATE.

Is Cyclododecyl Formate allowed in the EU?

Cyclododecyl Formate EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Cyclododecyl Formate do in cosmetics?

Cyclododecyl Formate functions as: Fragrance / perfuming agent. It is classified as a cosmetic ingredient in our database. CAS number: 59052-82-3.

What is the Margin of Safety for Cyclododecyl Formate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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