Regulatory Status
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Safety Data
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Expert Verdict
Low concern profile for macrocyclic musks generally. Potential skin sensitization at high concentrations typical of fragrance ingredients. IFRA may set use-level guidelines for related macrocyclic ketones.. 14-membered ring cyclic ketone with musky odor character; molecular formula C₁₄H₂₆O, molecular mass 210.36. Structurally related to cyclopentadecanone (exaltone, a 15-membered ring musk used as a substitute for natural animal musk). Macrocyclic musks are generally considered more environme...
Regulatory Flags
Frequently Asked Questions
Is Cyclotetradecanone safe in cosmetics?
Low concern profile for macrocyclic musks generally. Potential skin sensitization at high concentrations typical of fragrance ingredients. IFRA may set use-level guidelines for related macrocyclic ketones.. 14-membered ring cyclic ketone with musky odor character; molecular formula C₁₄H₂₆O, molecular mass 210.36. Structurally related to cyclopentadecanone (exaltone, a 15-membered ring musk used as a substitute for natural animal musk). Macrocyclic musks are generally considered more environme... The EU classifies Cyclotetradecanone as "permitted". Safety rating: MODERATE.
Is Cyclotetradecanone allowed in the EU?
Cyclotetradecanone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Cyclotetradecanone do in cosmetics?
Cyclotetradecanone functions as: Fragrance ingredient (macrocyclic musk ketone). It is classified as a cosmetic ingredient in our database. CAS number: 3603-99-4.
What is the Margin of Safety for Cyclotetradecanone?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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