Is Cytidine safe in cosmetics?
Cytidine has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Cytidine
INCI: CYTIDINE
Cytidine (CAS 65-46-3) is a cosmetic cosmetic ingredient functioning as Skin Conditioning, Skin Protecting. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 65-46-3 →
Auto-generated CPSR Part A draft with source citations
Function
Skin Conditioning, Skin Protecting
Safety Rating
EXCELLENT
Chemistry & Identifiers
IUPAC Name
4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
InChIKey
UHDGCWIWMRVCDJ-XVFCMESISA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
No specific restrictions; used as skin conditioning active
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Cytidine.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Humectant
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Cytidine.
Regulatory Flags
nucleoside
skin-conditioning
cell-communicating
natural-origin
Chemical Function
Humectant
Softener and conditioner
Regulatory Lists
Canada; pharmaceutical
Frequently Asked Questions
Is Cytidine allowed in the EU?
Cytidine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Cytidine do in cosmetics?
Cytidine functions as: Skin Conditioning, Skin Protecting. It is classified as a cosmetic ingredient in our database. CAS number: 65-46-3.
Is Cytidine used outside cosmetics?
Cytidine also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Cytidine compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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