Daphne Genkwa Bud Extract

INCI: DAPHNE GENKWA BUD EXTRACT

CAS Number
Not assigned (herbal bud extract)
Function
Traditional medicinal herb with diuretic, antitussive and anticancer uses; in cosmetics, positioned as bioactive plant extract.
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No cosmetic-specific rule, but Flos Genkwa is recognized as a toxic traditional herb; formulations containing significant levels of its diterpenoids would likely be considered unsafe/adulterated.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Contains daphnane-type diterpenes identified as key toxic components with mitochondrial toxicity and serious systemic effects; unsuitable for cosmetic use without deep purification and comprehensive toxicology assessment.

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Concern Level: High

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Daphne Genkwa Bud Extract safe in cosmetics?

Contains daphnane-type diterpenes identified as key toxic components with mitochondrial toxicity and serious systemic effects; unsuitable for cosmetic use without deep purification and comprehensive toxicology assessment. The EU classifies Daphne Genkwa Bud Extract as "permitted". Safety rating: POOR.

Is Daphne Genkwa Bud Extract allowed in the EU?

Daphne Genkwa Bud Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Daphne Genkwa Bud Extract do in cosmetics?

Daphne Genkwa Bud Extract functions as: Traditional medicinal herb with diuretic, antitussive and anticancer uses; in cosmetics, positioned as bioactive plant extract.. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned (herbal bud extract).

What is the Margin of Safety for Daphne Genkwa Bud Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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