Daphne Gnidium Leaf Extract

INCI: DAPHNE GNIDIUM LEAF EXTRACT

CAS Number
Not assigned (leaf extract)
Function
Investigated for antioxidant and antigenotoxic activity in experimental systems; any cosmetic use would likely rely on these properties.
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status restricted
US Notes No explicit cosmetic rule, but documented toxicity and severe effects after ingestion and skin exposure mean that significant inclusion in cosmetics would conflict with the requirement that products be safe.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

All parts of the plant are considered highly poisonous with symptoms including severe gastrointestinal and systemic effects following ingestion and dermatitis after skin contact; cosmetic use of crude or lightly processed leaf extract is strongly discouraged.

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Concern Level: High

Regulatory Flags

plant-extract natural-origin

Frequently Asked Questions

Is Daphne Gnidium Leaf Extract safe in cosmetics?

All parts of the plant are considered highly poisonous with symptoms including severe gastrointestinal and systemic effects following ingestion and dermatitis after skin contact; cosmetic use of crude or lightly processed leaf extract is strongly discouraged. The EU classifies Daphne Gnidium Leaf Extract as "prohibited". Safety rating: POOR.

Is Daphne Gnidium Leaf Extract allowed in the EU?

Daphne Gnidium Leaf Extract EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Daphne Gnidium Leaf Extract do in cosmetics?

Daphne Gnidium Leaf Extract functions as: Investigated for antioxidant and antigenotoxic activity in experimental systems; any cosmetic use would likely rely on these properties.. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned (leaf extract).

What is the Margin of Safety for Daphne Gnidium Leaf Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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