Is Dibromohexamidine Isethionate safe in cosmetics?
Dibromohexamidine Isethionate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Dibromohexamidine Isethionate
Also known as: Benzenecarboximidamide, 4,4'-[1,6-hexanediylbis(oxy)]bis[3-bromo-, bis(2-hydroxyethanesulfonate) (9CI), Dibromohexamidine- Isethionate, 3,3'-Dibromo-4,4'-hexamethylenedioxydi-benzamidine, Ethanesulfonic acid, 2-hydroxy-, compd. with 4,4'-[1,6-hexanediylbis(oxy)]bis[3-bromobenzenecarboximidamide] (2:1), EINECS 299-116-4
INCI: DIBROMOHEXAMIDINE ISETHIONATE
Dibromohexamidine Isethionate (CAS 93856-83-8) is a cosmetic cosmetic ingredient functioning as Preservative. EU Regulation 1223/2009 status: permitted, max 0.1%. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 93856-83-8 →
Auto-generated CPSR Part A draft with source citations
Function
Preservative
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
3-bromo-4-[6-(2-bromo-4-carbamimidoylphenoxy)hexoxy]benzenecarboximidamide;bis(2-hydroxyethanesulfonic acid)
InChIKey
LPAKTWBFZQIVQQ-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
EU Max Conc.
0.1%
US US Status
permitted
US Notes
Permitted — not prohibited under 21 CFR; manufacturer must substantiate safety
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Dibromohexamidine Isethionate.
Calculate MoS for your specific formulation with the MoS Calculator.
EU CosIng Annex Listing
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Annex V — Permitted Preservatives
Max: 0.1%
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
KR Korea MFDS Annex 2 (Restricted)
Category: Preservative. Max: 0.1% (as dibromohexamidine). —
SA Saudi SFDA (V - Preservatives)
Max: 0.001.
BRIN Brazil/India Cosmetics
Brazil: Permitted Preservative · max 0,1%
India: Permitted Preservative · max 0.001
Additional Jurisdictional Restrictions (3)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| IN | permitted_preservative | 0.1 | all cosmetics |
| BR | permitted_preservative | 0.1 | - |
| ASEAN | permitted_preservative | 0.1% | All products |
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Preservative
Regulatory List Membership (2)
EU Regulated in Personal Care
EU CosIng Cosmetics Ingredient Database
Expert Verdict
Expert safety assessment and concern-level summary for Dibromohexamidine Isethionate.
Regulatory Flags
potential-allergen
preservative
eu_cosing_listed
Known Synonyms
Benzenecarboximidamide, 4,4'-[1,6-hexanediylbis(oxy)]bis[3-bromo-, bis(2-hydroxyethanesulfonate) (9CI)
Dibromohexamidine- Isethionate
3,3'-Dibromo-4,4'-hexamethylenedioxydi-benzamidine
Ethanesulfonic acid, 2-hydroxy-, compd. with 4,4'-[1,6-hexanediylbis(oxy)]bis[3-bromobenzenecarboximidamide] (2:1)
EINECS 299-116-4
Chemical Function
Preservative
Regulatory Lists
Europe; Personal care
Frequently Asked Questions
Is Dibromohexamidine Isethionate allowed in the EU?
Dibromohexamidine Isethionate EU regulatory status: permitted. Maximum allowed concentration: 0.1%. This is based on EU Regulation 1223/2009 and its amendments.
What does Dibromohexamidine Isethionate do in cosmetics?
Dibromohexamidine Isethionate functions as: Preservative. It is classified as a cosmetic ingredient in our database. CAS number: 93856-83-8.
Is Dibromohexamidine Isethionate used outside cosmetics?
Dibromohexamidine Isethionate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Dibromohexamidine Isethionate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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