Is Dibutyl Oxalate safe in cosmetics?
Dibutyl Oxalate has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Dibutyl Oxalate
Also known as: Butyl ethanedioate, Butyl oxalate, Di-n-butyl oxalate, EINECS 218-092-8, NSC 8468 (+1 more)
Dibutyl Oxalate (CAS 2050-60-4) is a cosmetic cosmetic ingredient functioning as Chelating agent; Plasticizer; Softener and conditioner; Solvent. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 2050-60-4 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Dibutyl Oxalate is classified GHS Danger (H302, H314, H373, H315, H317, H318, H335) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Chelating agent; Plasticizer; Softener and conditioner; Solvent
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
dibutyl oxalate
InChIKey
JKRZOJADNVOXPM-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Dibutyl Oxalate.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Chelating agent
Plasticizer
Softener and conditioner
Solvent
Expert Verdict
Expert safety assessment and concern-level summary for Dibutyl Oxalate.
Known Synonyms
Butyl ethanedioate
Butyl oxalate
Di-n-butyl oxalate
EINECS 218-092-8
NSC 8468
UNII-S18C168OWC
Chemical Function
Solvent
Plasticizer
Chelating agent
Softener and conditioner
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3185643
Frequently Asked Questions
Is Dibutyl Oxalate allowed in the EU?
Dibutyl Oxalate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Dibutyl Oxalate do in cosmetics?
Dibutyl Oxalate functions as: Chelating agent; Plasticizer; Softener and conditioner; Solvent. It is classified as a cosmetic ingredient in our database. CAS number: 2050-60-4.
Is Dibutyl Oxalate used outside cosmetics?
Dibutyl Oxalate also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Dibutyl Oxalate have different safety status in cosmetics vs industrial chemicals?
Dibutyl Oxalate is classified GHS Danger (H302, H314, H373, H315, H317, H318, H335) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check Dibutyl Oxalate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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