Diisobutyl Oxalate

INCI: NOT A RECOGNIZED INCI COSMETIC INGREDIENT

CAS Number
2050-61-5
Function
Solvent / chemical intermediate (non-cosmetic)
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not regulated as a cosmetic ingredient

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Hydrolysis releases oxalic acid, which is nephrotoxic, corrosive, and a chelator of calcium; not intended for cosmetic use; would fail CPSR risk assessment without extensive de novo testing; classified for research use only

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Concern Level: High

Frequently Asked Questions

Is Diisobutyl Oxalate safe in cosmetics?

Hydrolysis releases oxalic acid, which is nephrotoxic, corrosive, and a chelator of calcium; not intended for cosmetic use; would fail CPSR risk assessment without extensive de novo testing; classified for research use only The EU classifies Diisobutyl Oxalate as "permitted". Safety rating: POOR.

Is Diisobutyl Oxalate allowed in the EU?

Diisobutyl Oxalate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Diisobutyl Oxalate do in cosmetics?

Diisobutyl Oxalate functions as: Solvent / chemical intermediate (non-cosmetic). It is classified as a cosmetic ingredient in our database. CAS number: 2050-61-5.

What is the Margin of Safety for Diisobutyl Oxalate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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