Diethyl Adipate

Also known as: BRN 1780035, 1,6-Diethyl hexanedioate, EINECS 205-477-0, Ethyl adipate, Ethyl delta-carboethoxyvalerate (+3 more)

INCI: DIETHYL ADIPATE

Diethyl Adipate (CAS 141-28-6) is a cosmetic cosmetic ingredient functioning as Fragrance, skin conditioning (emollient). EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.

View industrial chemical safety profile for CAS 141-28-6 →

Auto-generated CPSR Part A draft with source citations
Function
Fragrance, skin conditioning (emollient)
Safety Rating
GOOD

Chemistry & Identifiers

Formula
C10H18O4
MW
202.25 g/mol
EC Number
205-477-0
PubChem CID
8844
IUPAC Name
diethyl hexanedioate
InChIKey
VIZORQUEIQEFRT-UHFFFAOYSA-N

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes Permitted — not listed as prohibited or restricted under 21 CFR 700

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Diethyl Adipate.

Calculate MoS for your specific formulation with the MoS Calculator.

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type
Intermediate
Tonnage Band
Intermediate use only
Substance Type
SUBSTANCE
SVHC Candidate
No

PubChem Annotations

Safety and regulatory annotations from PubChem (NCBI) aggregated sources.

Safety (1)
Endocrine Disruptors
Potential endocrine disrupting compound
Source: NORMAN Suspect List Exchange

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Deodorizer Flavouring and nutrient Fragrance Softener and conditioner
Regulatory List Membership (1)
IFRA Fragrance Transparency List

Expert Verdict

Expert safety assessment and concern-level summary for Diethyl Adipate.

Regulatory Flags

fragrance-component endocrine_disruptor ifra_fragrance

Known Synonyms

BRN 1780035 1,6-Diethyl hexanedioate EINECS 205-477-0 Ethyl adipate Ethyl delta-carboethoxyvalerate NSC 19160 Diethylester kyseliny adipove UNII-7B19K45L6C

Chemical Function

Softener and conditioner Deodorizer Flavouring and nutrient Fragrance

Regulatory Lists

Europe IFRA Transparency

Australian Status

AICIS status: listed

Frequently Asked Questions

Is Diethyl Adipate safe in cosmetics?

Diethyl Adipate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.

Is Diethyl Adipate allowed in the EU?

Diethyl Adipate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Diethyl Adipate do in cosmetics?

Diethyl Adipate functions as: Fragrance, skin conditioning (emollient). It is classified as a cosmetic ingredient in our database. CAS number: 141-28-6.

Is Diethyl Adipate used outside cosmetics?

Diethyl Adipate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

Related Ingredients

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Excellent Same category
Fragrance
Acetoin
Excellent Same category
Skin conditioning, fragrance
(AGARICUS BLAZEI FERMENT + GANODERMA LUCIDUM FERMENT + GANODERMA MULTIPILEUM FERMENT) EXTRACT
Good Similar safety
Anti-sebum, Antioxidant, Skin Protecting
(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA) ROOT/CNIDIUM OFFICINALE RHIZOME EXTRACT
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Skin Conditioning, Skin Conditioning ...
(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA/SCUTELLARIA BAICALENSIS) ROOT/(CNIDIUM OFFICINALE/COPTIS CHINENSIS) RHIZOME/GARDENIA JASMINOIDES FRUIT/PHELLODENDRON CHINENSE BARK EXTRACT
Good Similar safety
(ANGELICA GIGAS/GLYCYRRHIZA URALENSIS/REHMANNIA GLUTINOSA ROOT)/ANGELICA GIGAS STEM/CARTHAMUS TINCTORIUS FLOWER/(CARTHAMUS TINCTORIUS/PRUNUS PERSICA SEED)PORIA COCOS WATER
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Humectant, Skin Conditioning, Skin Pr...
(ANGELICA KEISKEI/CHRYSANTHEMUM ZAWADSKII) LEAF/STEM/CINNAMOMUM CASSIA BARK/TRICHOSANTES KIRILOWII FRUIT/ULMUS DAVIDIANA BARK/ROOT/(PAEONIA JAPONICA/BUPLEURUM FALCATUM/POLYGALA TENUIFOLIA ROOT)/VISCUS ALBUM STEM EXTRACT
Good Similar safety
Anti-seborrheic, Anti-sebum, Antioxid...
(APPLE/CITRUS JUNOS/LENTIL/PEAR/PUMPKIN/STRAWBERRY/TOMATO FRUIT)/CORN KERNEL/(ARCTIUM LAPPA/BRASSICA OLERACEA ACEPHALA/CABBAGE/CAMELLIA SINENSIS/MORINGA OLEIFERA/RADISH/SPINACH LEAF)/(SORGHUM BICOLOR LEAF/STEM)/OAT MEAL/POTATO PULP/(CARROT/NELUMBO NUCIFERA/RADISH/WILD YAM ROOT)/(AMARANTHUS HYPOCHONDRIACUS/CASHEW/CICER ARIETINUM/COIX LACRYMA-JOBI MA-YUEN /MACADAMIA TERNIFOLIA/PHASEOLUS ANGULARIS/PISTACIA VERA/RHYNCHOSIA NULUBILIS/RICE/SESAME/SETARIA ITALICA/SOYBEAN/SWEET ALMOND/WHEAT SEED)/HORDEUM VULGARE SPROUT/CYPERUS ESCULENTUS TUBER/ARTEMISIA PRINCEPS/BROCCOLI/CHENOPODIUM QUINOA/ENTEROMORPHA COMPRESSA/HORDEUM VULGARE/IPOMOEA BATATAS/LAMINARIA JAPONICA/LENTINUS EDODES/PLEUROTUS OSTREATUS/PORPHYRA TENERA/UNDARIA PINNATIFIDA EXTRACT
Good Similar safety
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