Is Diethyl Ketoglutarate safe in cosmetics?
Diethyl Ketoglutarate has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Diethyl Ketoglutarate
INCI: DIETHYL KETOGLUTARATE
Diethyl Ketoglutarate (CAS 13192-04-6) is a cosmetic cosmetic ingredient functioning as Skin conditioning. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 13192-04-6 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
dimethyl 2-oxopentanedioate
InChIKey
TXIXSLPEABAEHP-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — not restricted under 21 CFR
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Diethyl Ketoglutarate.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Diethyl Ketoglutarate.
Regulatory Lists
Cons electronics mech appliances and machinery; detected; Europe
Frequently Asked Questions
Is Diethyl Ketoglutarate allowed in the EU?
Diethyl Ketoglutarate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Diethyl Ketoglutarate do in cosmetics?
Diethyl Ketoglutarate functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 13192-04-6.
Is Diethyl Ketoglutarate used outside cosmetics?
Diethyl Ketoglutarate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Diethyl Ketoglutarate compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Related Ingredients
1-Methylhydantoin-2-imide (Creatinine)
Excellent
Same category
Skin conditioning (skin brightening/l...
4-Amino-3-Hydroxybutyric Acid
Excellent
Same category
Skin Conditioning
Acetyl Glycyl Beta-Alanine
Excellent
Same category
Skin conditioning agent with melanin ...
Acetyl Tripeptide-1
Excellent
Same category
Skin Conditioning
Acetylneuraminic Acid
Excellent
Same category
Skin Conditioning, Skin Protecting
Acetylphytosphingosine
Excellent
Same category
Skin Conditioning, Hair Conditioning;...
(20S)-Protopanaxadiol
Moderate
Similar safety
(Cryptomeria Japonica/Chamaecyparis Obtusa) Stem Ferment Extract
Moderate
Similar safety
Antimicrobial, antioxidant, humectant
(Licorice/Reynoutria Japonica) Root/Stem Extract
Moderate
Similar safety
Skin conditioning, antioxidant
(SH-Pentapeptide-10 6-Aminocaprooyl SH-Pentapeptide-11) SP
Moderate
Similar safety
Skin/hair conditioning (peptide-based...
1,2,3,4,4a,5,6,7-Octahydro-2,5,5-Trimethyl-2-Naphthol
Moderate
Similar safety
Fragrance ingredient
1,2,3,4,4a,7,8,8a-Octahydro-2,4a,5,8a-Tetramethyl-Naphthyl Formate
Moderate
Similar safety
Fragrance ingredient
Disodium Lauryl Sulfosuccinate
Good
Chemical family
Surfactant, Cleansing, Emulsifying, F...
DIETHANOLAMINE
Moderate
Browse nearby
Buffering
DIETHYL PHTHALATE
Good
Browse nearby
Denaturant, Film Forming, Fragrance, ...
Is Diethyl Ketoglutarate in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Diethyl Ketoglutarate in your formulation.