Diethylene Glycol Dibenzoate
INCI: DIETHYLENE GLYCOL DIBENZOATE
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
3 study endpoints found for Diethylene Glycol Dibenzoate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 0.20000000298 % | oral | rat | Subchronic | COSMOS_DB |
| LOAEL | 1 % | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 414 mg/kg bw/day | oral | dog | Subchronic | COSMOS_DB |
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Expert Verdict
GHS H320: causes eye irritation; oral toxicity studies in rats showed convulsions and liver changes; critical: must verify free diethylene glycol (DEG) content <0.1% per EU guidance; primarily used as industrial plasticizer—CPSR assessor must justify cosmetic necessity; WGK Germany: 2 (water hazard class)
Frequently Asked Questions
Is Diethylene Glycol Dibenzoate safe in cosmetics?
GHS H320: causes eye irritation; oral toxicity studies in rats showed convulsions and liver changes; critical: must verify free diethylene glycol (DEG) content <0.1% per EU guidance; primarily used as industrial plasticizer—CPSR assessor must justify cosmetic necessity; WGK Germany: 2 (water hazard class) The EU classifies Diethylene Glycol Dibenzoate as "permitted". Safety rating: MODERATE. 3 toxicological study endpoint(s) are available in our database.
Is Diethylene Glycol Dibenzoate allowed in the EU?
Diethylene Glycol Dibenzoate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Diethylene Glycol Dibenzoate do in cosmetics?
Diethylene Glycol Dibenzoate functions as: Plasticizer, solvent, perfume stabilizer. It is classified as a cosmetic ingredient in our database. CAS number: 120-55-8.
What is the Margin of Safety for Diethylene Glycol Dibenzoate?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Diethylene Glycol Dibenzoate?
The NOAEL (No Observed Adverse Effect Level) for Diethylene Glycol Dibenzoate is 0.20000000298 % based on a Subchronic study via oral route in rat. A total of 3 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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