Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for Benzyl Isoeugenol. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 120 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
Expert Verdict
Potential metabolic release of isoeugenol with cross-reactivity in isoeugenol-sensitized individuals; mandatory allergen declaration may apply under expanded EU allergen list; DPRA/KeratinoSens testing strongly recommended.
Regulatory Flags
Frequently Asked Questions
Is Benzyl Isoeugenol safe in cosmetics?
Potential metabolic release of isoeugenol with cross-reactivity in isoeugenol-sensitized individuals; mandatory allergen declaration may apply under expanded EU allergen list; DPRA/KeratinoSens testing strongly recommended. The EU classifies Benzyl Isoeugenol as "prohibited". Safety rating: MODERATE. 1 toxicological study endpoint(s) are available in our database.
Is Benzyl Isoeugenol allowed in the EU?
Benzyl Isoeugenol EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Benzyl Isoeugenol do in cosmetics?
Benzyl Isoeugenol functions as: Perfuming (fragrance ingredient). It is classified as a cosmetic ingredient in our database. CAS number: 120-11-6.
What is the Margin of Safety for Benzyl Isoeugenol?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Benzyl Isoeugenol?
The NOAEL (No Observed Adverse Effect Level) for Benzyl Isoeugenol is 120 mg/kg bw/day based on a Short Term Toxicity study via oral route in rat. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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