Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for Diethylhexyl Succinate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 500 mg/kg bw/day | dermal | code:3484 | dermal | REACH |
Expert Verdict
Safe in present practices of use per CIR 2012 group assessment. Safety based on read-across from dicarboxylic acid ester group.
Frequently Asked Questions
Is Diethylhexyl Succinate safe in cosmetics?
Safe in present practices of use per CIR 2012 group assessment. Safety based on read-across from dicarboxylic acid ester group. The EU classifies Diethylhexyl Succinate as "permitted". Safety rating: GOOD. 1 toxicological study endpoint(s) are available in our database.
Is Diethylhexyl Succinate allowed in the EU?
Diethylhexyl Succinate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Diethylhexyl Succinate do in cosmetics?
Diethylhexyl Succinate functions as: Emollient, Skin Conditioning, Solvent. It is classified as a Emollient in our database. CAS number: 27247-96-7.
What is the Margin of Safety for Diethylhexyl Succinate?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Diethylhexyl Succinate?
The NOAEL (No Observed Adverse Effect Level) for Diethylhexyl Succinate is 500 mg/kg bw/day based on a dermal study via dermal route in code:3484. Source: REACH.
Compliance Tools
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Related Ingredients
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