Dihydro Pentamethylindanone (DPMI / Cashmeran)

INCI: 6,7-DIHYDRO-1,1,2,3,3-PENTAMETHYL-4(5H)-INDANONE

CAS Number
33704-61-9
Function
Fragrance ingredient — synthetic musk/amber/woody note
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — no specific CFR restriction; RIFM safety assessment available

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Dermal sensitization and systemic toxicity are the driving endpoints for IFRA restrictions. Must comply with IFRA category-specific limits. Requires IFRA Certificate of Conformity from fragrance supplier. EU fragrance allergen labelling may apply depending on category.

⚠️
Concern Level: High

Regulatory Flags

potential-allergen fragrance-component ifra_fragrance

Frequently Asked Questions

Is Dihydro Pentamethylindanone (DPMI / Cashmeran) safe in cosmetics?

Dermal sensitization and systemic toxicity are the driving endpoints for IFRA restrictions. Must comply with IFRA category-specific limits. Requires IFRA Certificate of Conformity from fragrance supplier. EU fragrance allergen labelling may apply depending on category. The EU classifies Dihydro Pentamethylindanone (DPMI / Cashmeran) as "permitted". Safety rating: MODERATE.

Is Dihydro Pentamethylindanone (DPMI / Cashmeran) allowed in the EU?

Dihydro Pentamethylindanone (DPMI / Cashmeran) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Dihydro Pentamethylindanone (DPMI / Cashmeran) do in cosmetics?

Dihydro Pentamethylindanone (DPMI / Cashmeran) functions as: Fragrance ingredient — synthetic musk/amber/woody note. It is classified as a cosmetic ingredient in our database. CAS number: 33704-61-9.

What is the Margin of Safety for Dihydro Pentamethylindanone (DPMI / Cashmeran)?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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