Also known as: 4H-Inden-4-one, 1,2,3,5,6,7-hexahydro-1,1,2,3,3-pentamethyl-, 1,2,3,5,6,7-Hexahydro-1,1,2,3,3-pentamethyl-4H-inden-4-one, 6,7-Dihydro-1,1,2,3,3-pentamethyl-4-(5H)indanone, EINECS 251-649-3, UNII-BZR4438MY4 (+2 more)
INCI: 6,7-DIHYDRO-1,1,2,3,3-PENTAMETHYL-4(5H)-INDANONE
Dihydro Pentamethylindanone (DPMI / Cashmeran) (CAS 33704-61-9) is a cosmetic cosmetic ingredient functioning as Fragrance ingredient — synthetic musk/amber/woody note. Reported NOAEL =10 mg/kg bw/day in Rat (ECHA); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 33704-61-9 →
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Margin of Safety, dermal absorption, and sensitization profile summaries for Dihydro Pentamethylindanone (DPMI / Cashmeran).
Calculate MoS for your specific formulation with the MoS Calculator.
1 study endpoint found for Dihydro Pentamethylindanone (DPMI / Cashmeran). NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =10 mg/kg bw/day | oral | Rat | subchronic | ECHA |
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Preliminary editorial summary for Dihydro Pentamethylindanone (DPMI / Cashmeran) — not a computed safety verdict. See the sourced toxicological data above.
Public NOAEL study rows linked to Dihydro Pentamethylindanone (DPMI / Cashmeran) by CAS number or substance name.
Same-CAS public records found in pharmaceutical data.
Same-CAS rows from the pharmaceutical spoke database.
Dihydro Pentamethylindanone (DPMI / Cashmeran) has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted. 1 toxicological study endpoint(s) are available in our database.
Dihydro Pentamethylindanone (DPMI / Cashmeran) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
Dihydro Pentamethylindanone (DPMI / Cashmeran) functions as: Fragrance ingredient — synthetic musk/amber/woody note. It is classified as a cosmetic ingredient in our database. CAS number: 33704-61-9.
The NOAEL (No Observed Adverse Effect Level) for Dihydro Pentamethylindanone (DPMI / Cashmeran) is =10 mg/kg bw/day based on a subchronic study via oral route in Rat. Source: ECHA.
Dihydro Pentamethylindanone (DPMI / Cashmeran) also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
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