Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Expert Verdict
Secondary alkanolamine with risk of nitrosamine formation if used with N-nitrosating agents; declining use in formulations; subchronic oral NOAEL 100–500 mg/kg bw/d.
Frequently Asked Questions
Is Diisopropanolamine safe in cosmetics?
Secondary alkanolamine with risk of nitrosamine formation if used with N-nitrosating agents; declining use in formulations; subchronic oral NOAEL 100–500 mg/kg bw/d. The EU classifies Diisopropanolamine as "permitted". Safety rating: GOOD.
Is Diisopropanolamine allowed in the EU?
Diisopropanolamine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Diisopropanolamine do in cosmetics?
Diisopropanolamine functions as: pH adjuster / buffering agent. It is classified as a cosmetic ingredient in our database. CAS number: 110-97-4.
What is the Margin of Safety for Diisopropanolamine?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
Check Diisopropanolamine compliance across multiple jurisdictions:
Related Ingredients
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