Is Diisopropyl Sebacate safe in cosmetics?
Diisopropyl Sebacate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Diisopropyl Sebacate
INCI: DIISOPROPYL SEBACATE
Diisopropyl Sebacate (CAS 7491-02-3) is a cosmetic cosmetic ingredient functioning as Emollient. EU Regulation 1223/2009 status: permitted, max 10%. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 7491-02-3 →
Auto-generated CPSR Part A draft with source citations
Function
Emollient
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
dipropan-2-yl decanedioate
InChIKey
XFKBBSZEQRFVSL-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
EU Max Conc.
10%
US US Status
permitted
US Notes
Circle substance on the Safer Chemical Ingredients List (SCIL), meaning it has been verified to be of low concern based on experimental and modelled data.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Diisopropyl Sebacate.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100 - 1,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Typical Use Concentrations
Reported concentration ranges per product category from SCCS/CIR/industry sources.
| Product Category | Typical Range | Max Reported | Source |
|---|---|---|---|
| Lipstick | 5–15 | 20 | CIR |
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Fragrance
Plasticizer
Softener and conditioner
Solvent
Regulatory List Membership (1)
IFRA Fragrance Transparency List
Expert Verdict
Expert safety assessment and concern-level summary for Diisopropyl Sebacate.
Regulatory Flags
ifra_fragrance
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Diisopropyl Sebacate by CAS number or substance name.
Studies
18
Lowest NOAEL
178 mg/kg bw/day
Highest NOAEL
2187 mg/kg bw/day
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip
Chemical Function
Solvent
Softener and conditioner
Plasticizer
Fragrance
Regulatory Lists
IFRA Transparency
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Diisopropyl Sebacate allowed in the EU?
Diisopropyl Sebacate EU regulatory status: permitted. Maximum allowed concentration: 10%. This is based on EU Regulation 1223/2009 and its amendments.
What does Diisopropyl Sebacate do in cosmetics?
Diisopropyl Sebacate functions as: Emollient. It is classified as a cosmetic ingredient in our database. CAS number: 7491-02-3.
Compliance Tools
Check Diisopropyl Sebacate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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