Dulbecco's Phosphate Buffered Saline

INCI: DULBECCO'S PHOSPHATE BUFFERED SALINE

CAS Number
N/A — multi-component solution (NaCl, KCl, Na₂HPO₄, KH₂PO₄)
Function
Buffering agent (maintains formulation pH ≈ 7.4)
Safety Rating
EXCELLENT

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — component salts are GRAS; no 21 CFR restriction for cosmetic use

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

No significant safety concerns; ensure sterility in formulation to prevent microbial growth and confirm compatibility with chelation-sensitive actives.

⚠️
Concern Level: Low

Frequently Asked Questions

Is Dulbecco's Phosphate Buffered Saline safe in cosmetics?

No significant safety concerns; ensure sterility in formulation to prevent microbial growth and confirm compatibility with chelation-sensitive actives. The EU classifies Dulbecco's Phosphate Buffered Saline as "permitted". Safety rating: EXCELLENT.

Is Dulbecco's Phosphate Buffered Saline allowed in the EU?

Dulbecco's Phosphate Buffered Saline EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Dulbecco's Phosphate Buffered Saline do in cosmetics?

Dulbecco's Phosphate Buffered Saline functions as: Buffering agent (maintains formulation pH ≈ 7.4). It is classified as a cosmetic ingredient in our database. CAS number: N/A — multi-component solution (NaCl, KCl, Na₂HPO₄, KH₂PO₄).

What is the Margin of Safety for Dulbecco's Phosphate Buffered Saline?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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