Is Ethyl 2-Methylbutyrate safe in cosmetics?
Ethyl 2-Methylbutyrate has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Ethyl 2-Methylbutyrate
INCI: ETHYL 2-METHYLBUTYRATE
Ethyl 2-Methylbutyrate (CAS 7452-79-1 [^1_11][^1_12]) is a cosmetic cosmetic ingredient functioning as Fragrance / Flavoring agent. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 7452-79-1 [^1_11][^1_12] →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance / Flavoring agent
Safety Rating
EXCELLENT
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — FEMA GRAS #2443; FDA accepted for food use
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Ethyl 2-Methylbutyrate.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Ethyl 2-Methylbutyrate.
Regulatory Flags
fragrance-component
epa_safer_alternative
ifra_fragrance
fda_food_additive
jecfa_safe
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Ethyl 2-Methylbutyrate by CAS number or substance name.
Studies
4
Lowest NOAEL
1000 mg/kg bw/day
Highest NOAEL
1000 mg/kg bw/day
ToxValDB_ECHA_IUCLID
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip
Frequently Asked Questions
Is Ethyl 2-Methylbutyrate allowed in the EU?
Ethyl 2-Methylbutyrate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Ethyl 2-Methylbutyrate do in cosmetics?
Ethyl 2-Methylbutyrate functions as: Fragrance / Flavoring agent. It is classified as a cosmetic ingredient in our database. CAS number: 7452-79-1 [^1_11][^1_12].
Compliance Tools
Check Ethyl 2-Methylbutyrate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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