Ethyl Methoxycinnamate

INCI: ETHYL METHOXYCINNAMATE

CAS Number
24393-56-4 (ethyl 4-methoxycinnamate — distinct from Ethylhexyl Methoxycinnamate CAS 5466-77-3)
Function
UV absorber / UV filter
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Not FDA-approved as a sunscreen active. Only Octinoxate (Ethylhexyl Methoxycinnamate CAS 5466-77-3) is listed in 21 CFR 352.10.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
high
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Not an authorized UV filter in EU or US. Regulatory non-compliance if claimed as sun protection. Parent compound exhibits endocrine activity (estrogenic and weak anti-androgenic effects). Higher dermal absorption expected compared to Ethylhexyl Methoxycinnamate due to smaller ester chain. Cinnamate sensitization risk present. UV protection claims are not permitted without Annex VI listing.

⚠️
Concern Level: High

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Ethyl Methoxycinnamate safe in cosmetics?

Not an authorized UV filter in EU or US. Regulatory non-compliance if claimed as sun protection. Parent compound exhibits endocrine activity (estrogenic and weak anti-androgenic effects). Higher dermal absorption expected compared to Ethylhexyl Methoxycinnamate due to smaller ester chain. Cinnamate sensitization risk present. UV protection claims are not permitted without Annex VI listing. The EU classifies Ethyl Methoxycinnamate as "permitted". Safety rating: MODERATE.

Is Ethyl Methoxycinnamate allowed in the EU?

Ethyl Methoxycinnamate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ethyl Methoxycinnamate do in cosmetics?

Ethyl Methoxycinnamate functions as: UV absorber / UV filter. It is classified as a cosmetic ingredient in our database. CAS number: 24393-56-4 (ethyl 4-methoxycinnamate — distinct from Ethylhexyl Methoxycinnamate CAS 5466-77-3).

What is the Margin of Safety for Ethyl Methoxycinnamate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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