Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
10 study endpoints found for Ethyl Methylphenylglycidate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 250 mg/kg bw/day | oral | rat | Chronic | COSMOS_DB |
| NOAEL | 50 mg/kg bw/day | oral | rat | Chronic | COSMOS_DB |
| NOAEL | 125 mg/kg bw/day | oral | rat | Chronic | COSMOS_DB |
| NOAEL | 500 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 195 mg/kg bw/day | oral | rat | Chronic | COSMOS_DB |
| NOAEL | 195 mg/kg bw/day | oral | rat | Carcinogenicity | COSMOS_DB |
| NOAEL | 250 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| dose_tested | 125 mg/kg bw/day | oral | rat | Chronic | COSMOS_DB |
| NOAEL | 500 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >1000 mg/kg bw/day | dermal | rat | dermal | REACH |
Expert Verdict
GHS-classified skin irritant and eye irritant at concentrate levels; epoxide moiety warrants in-use concentration limits; must comply with IFRA standards for finished product levels
Regulatory Flags
Frequently Asked Questions
Is Ethyl Methylphenylglycidate safe in cosmetics?
GHS-classified skin irritant and eye irritant at concentrate levels; epoxide moiety warrants in-use concentration limits; must comply with IFRA standards for finished product levels The EU classifies Ethyl Methylphenylglycidate as "restricted". Safety rating: GOOD. 10 toxicological study endpoint(s) are available in our database.
Is Ethyl Methylphenylglycidate allowed in the EU?
Ethyl Methylphenylglycidate EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does Ethyl Methylphenylglycidate do in cosmetics?
Ethyl Methylphenylglycidate functions as: Fragrance (also known as Strawberry Aldehyde / Aldehyde C-16). It is classified as a cosmetic ingredient in our database. CAS number: 77-83-8.
What is the Margin of Safety for Ethyl Methylphenylglycidate?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Ethyl Methylphenylglycidate?
The NOAEL (No Observed Adverse Effect Level) for Ethyl Methylphenylglycidate is 250 mg/kg bw/day based on a Chronic study via oral route in rat. A total of 10 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
Check Ethyl Methylphenylglycidate compliance across multiple jurisdictions:
Related Ingredients
Is Ethyl Methylphenylglycidate in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Ethyl Methylphenylglycidate in your formulation.