Is Ethyl PCA safe in cosmetics?
Ethyl PCA has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
EXCELLENT
Cosmetic Ingredient
Ethyl PCA
INCI: ETHYL PCA
Ethyl PCA (CAS 7149-65-7 (ethyl pyroglutamate)) is a cosmetic cosmetic ingredient functioning as Humectant / Skin conditioning agent. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 7149-65-7 (ethyl pyroglutamate) →
Function
Humectant / Skin conditioning agent
Editorial assessment
EXCELLENT
Preliminary editorial note — not a computed safety verdict.
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — CIR concluded PCA and its salts/esters are safe as used
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Ethyl PCA.
Calculate MoS for your specific formulation with the MoS Calculator.
Editorial summary
Preliminary editorial summary for Ethyl PCA — not a computed safety verdict. See the sourced toxicological data above.
Frequently Asked Questions
Is Ethyl PCA allowed in the EU?
Ethyl PCA EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Ethyl PCA do in cosmetics?
Ethyl PCA functions as: Humectant / Skin conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: 7149-65-7 (ethyl pyroglutamate).
Compliance Tools
Check Ethyl PCA compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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Chemical family
Perfuming
ETHOXY-METHOXYMETHYL-PHENOL
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Browse nearby
Perfuming
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Solvent
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