Good Cosmetic Ingredient NOAEL Data

Ethyl Pelargonate

INCI: ETHYL PELARGONATE

CAS Number
123-29-5
Function
Fragrance agent / Emollient
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” FEMA GRAS status; no CFR cosmetic restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

2 study endpoints found for Ethyl Pelargonate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 1000 mg/kg bw/day oral rat Subchronic COSMOS_DB
dose_tested 1000 mg/kg bw/day oral rat Subchronic COSMOS_DB

Expert Verdict

Limited dedicated cosmetic toxicological data; used primarily at low levels as part of fragrance blends.

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Concern Level: Low

Regulatory Flags

fragrance-component ifra_fragrance fda_food_additive

Frequently Asked Questions

Is Ethyl Pelargonate safe in cosmetics?

Limited dedicated cosmetic toxicological data; used primarily at low levels as part of fragrance blends. The EU classifies Ethyl Pelargonate as "permitted". Safety rating: GOOD. 2 toxicological study endpoint(s) are available in our database.

Is Ethyl Pelargonate allowed in the EU?

Ethyl Pelargonate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ethyl Pelargonate do in cosmetics?

Ethyl Pelargonate functions as: Fragrance agent / Emollient. It is classified as a cosmetic ingredient in our database. CAS number: 123-29-5.

What is the Margin of Safety for Ethyl Pelargonate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Ethyl Pelargonate?

The NOAEL (No Observed Adverse Effect Level) for Ethyl Pelargonate is 1000 mg/kg bw/day based on a Subchronic study via oral route in rat. A total of 2 study endpoints are available. Source: COSMOS_DB.

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