Ethyl Tafluprostamide

INCI: ETHYL TAFLUPROSTAMIDE

CAS Number
1185851-52-8
Function
Hair conditioning (eyelash/eyebrow growth stimulation)
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status restricted
US Notes Currently permitted โ€” not specifically restricted under 21 CFR; CIR review ongoing

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

HIGH RISK. Prostaglandin F2ฮฑ analog with documented adverse effects including iris color change (irreversible), periorbital fat atrophy, eyelid hyperpigmentation, and increased intraocular pressure changes. SCCS declared unsafe July 2025. EU ban expected. Do NOT formulate without legal review.

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Concern Level: High

Frequently Asked Questions

Is Ethyl Tafluprostamide safe in cosmetics?

HIGH RISK. Prostaglandin F2ฮฑ analog with documented adverse effects including iris color change (irreversible), periorbital fat atrophy, eyelid hyperpigmentation, and increased intraocular pressure changes. SCCS declared unsafe July 2025. EU ban expected. Do NOT formulate without legal review. The EU classifies Ethyl Tafluprostamide as "prohibited". Safety rating: POOR.

Is Ethyl Tafluprostamide allowed in the EU?

Ethyl Tafluprostamide EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Ethyl Tafluprostamide do in cosmetics?

Ethyl Tafluprostamide functions as: Hair conditioning (eyelash/eyebrow growth stimulation). It is classified as a cosmetic ingredient in our database. CAS number: 1185851-52-8.

What is the Margin of Safety for Ethyl Tafluprostamide?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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