Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
4 study endpoints found for Ethylene Dodecanedioate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | >=1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 300 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 3000 mg/kg bw/day | oral | mouse | oral | REACH |
| NOAEL | 3000 mg/kg bw/day | oral | - | oral | REACH |
Expert Verdict
Not genotoxic; not phototoxic; no developmental or reproductive hazard flags
Regulatory Flags
Frequently Asked Questions
Is Ethylene Dodecanedioate safe in cosmetics?
Not genotoxic; not phototoxic; no developmental or reproductive hazard flags The EU classifies Ethylene Dodecanedioate as "permitted". Safety rating: EXCELLENT. 4 toxicological study endpoint(s) are available in our database.
Is Ethylene Dodecanedioate allowed in the EU?
Ethylene Dodecanedioate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Ethylene Dodecanedioate do in cosmetics?
Ethylene Dodecanedioate functions as: Fragrance / masking agent. It is classified as a cosmetic ingredient in our database. CAS number: 54982-83-1.
What is the Margin of Safety for Ethylene Dodecanedioate?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Ethylene Dodecanedioate?
The NOAEL (No Observed Adverse Effect Level) for Ethylene Dodecanedioate is >=1000 mg/kg bw/day based on a oral study via oral route in rat. A total of 4 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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