Is EUCALYPTUS CITRIODORA OIL safe in cosmetics?
EUCALYPTUS CITRIODORA OIL has a safety rating of "GOOD" in our database. EU status: permitted. 10 toxicological study endpoint(s) are available in our database.
EUCALYPTUS CITRIODORA OIL
Also known as: Eucalyptus oil, Oils, eucalyptus, Caswell No. 618A, EPA Pesticide Chemical Code 040503, Eucalyptus absolute (+13 more)
EUCALYPTUS CITRIODORA OIL (CAS 8000-48-4) is a cosmetic cosmetic ingredient functioning as Fragrance, Tonic. Reported NOAEL =100 mg/kg bw/day in rat (CIR Safety Assessment); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical and food safety data.
Function
Fragrance, Tonic
Editorial assessment
GOOD
Preliminary editorial note — not a computed safety verdict.
Regulatory Status
EU EU Status
permitted
US US Status
Not specifically regulated
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Toxicological Studies
10 study endpoints found for EUCALYPTUS CITRIODORA OIL. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =100 mg/kg bw/day | - | rat | NOAEL study | CIR Safety Assessment |
| NOAEL | =100 mg/kg bw/day | - | rat | NOAEL study | CIR Safety Assessment |
| NOAEL | =100 mg/kg bw/day | - | rat | NOAEL study | CIR Safety Assessment |
| NOAEL | =100 mg/kg bw/day | - | rat | NOAEL study | CIR Safety Assessment |
| NOAEL | =300 mg/kg | oral | rat | oral toxicity | CIR Safety Assessment |
| NOAEL | =300 mg/kg | oral | rat | oral toxicity | CIR Safety Assessment |
| NOAEL | =300 mg/kg | oral | rat | oral toxicity | CIR Safety Assessment |
| NOAEL | =300 mg/kg | oral | rat | oral toxicity | CIR Safety Assessment |
| NOAEL | =1000 mg/kg | oral | rat | oral toxicity | CIR Safety Assessment |
| NOAEL | =1000 mg/kg | oral | rat | oral toxicity | CIR Safety Assessment |
EPA ToxValDB — Toxicity Values
3 toxicity values from EPA ToxValDB (aggregated from CCTE, HPV, ToxRefDB, IRIS, and other regulatory dossiers).
| Endpoint | Value | Species | Route | Duration | Source |
|---|---|---|---|---|---|
| LD50 | <5000 mg/kg | Rabbit | dermal | acute | ECHA |
| LD50 | =2480 mg/kg | Rabbit | dermal | acute | ECHA |
| LD50 | =2480 mg/kg | Rat | oral | - | TEST |
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
Additional Jurisdictional Restrictions (1)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| CA | restricted | 25% | All cosmetics |
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Biocide
Deodorizer
Flavouring and nutrient
Fragrance
Humectant
Pharmaceutical
Softener and conditioner
Regulatory List Membership (5)
EU Regulated in Personal Care
EU Restricted for Children (Cosmetics)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Consumer Product Chemical
Editorial summary
Preliminary editorial summary for EUCALYPTUS CITRIODORA OIL — not a computed safety verdict. See the sourced toxicological data above.
Regulatory Flags
cosing-sourced
eu-permitted
fragrance
needs-enrichment
eu_children_restricted
ifra_fragrance
fda_food_additive
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to EUCALYPTUS CITRIODORA OIL by CAS number or substance name.
Studies
12
Lowest NOAEL
100
Highest NOAEL
1000
Units vary across source rows: mg/kg bw/day, mg/kg
CIR Safety Assessment
Known Synonyms
Eucalyptus oil
Oils, eucalyptus
Caswell No. 618A
EPA Pesticide Chemical Code 040503
Eucalyptus absolute
Eucalyptus citriodora
Eucalyptus citriodora distillate
Eucalyptus globulus oil
Eucalyptus oil citriodora
FEMA No. 2466
Oil eucalyptus globulus or macarthuri
Essential oils, eucalyptus
Oils, essential, eucalyptus
Essential eucalyptus oil
Eucalyptus terpene oil
Eukalyptus oel
UNII-2R04ONI662
UNII-M63U6N96EB
Chemical Function
Fragrance
Regulatory Lists
IFRA Transparency
IFRA Transparency
consumer_product
IFRA Transparency
IFRA Transparency
IFRA Transparency
Europe; Personal care
Europe; Personal care
Europe; Personal care
Europe; Personal care
children; Europe; Personal care
children; Europe; Personal care - specialized bath products - bubble bath
IFRA Transparency
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical and food safety data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA count match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Adverse Event Associations
26
SOURCE
EFSA / FDA GRAS
food_additives
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
EUCALYPTUS, OIL (EUCALYPTUS GLOBULUS LABILLE)
Food Category
flavoring
Frequently Asked Questions
Is EUCALYPTUS CITRIODORA OIL allowed in the EU?
EUCALYPTUS CITRIODORA OIL EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does EUCALYPTUS CITRIODORA OIL do in cosmetics?
EUCALYPTUS CITRIODORA OIL functions as: Fragrance, Tonic. It is classified as a cosmetic ingredient in our database. CAS number: 8000-48-4.
What is the NOAEL for EUCALYPTUS CITRIODORA OIL?
The NOAEL (No Observed Adverse Effect Level) for EUCALYPTUS CITRIODORA OIL is =100 mg/kg bw/day based on a NOAEL study study via oral route in rat. A total of 10 study endpoints are available. Source: CIR Safety Assessment.
Is EUCALYPTUS CITRIODORA OIL used outside cosmetics?
EUCALYPTUS CITRIODORA OIL also appears in pharmaceutical and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check EUCALYPTUS CITRIODORA OIL compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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