Farnesene

INCI: FARNESENE

CAS Number
502-61-4 (mixture of isomers)
Function
Fragrance ingredient, skin conditioning
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” FEMA GRAS 3839

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

GHS Category 2 skin irritant and Category 2A eye irritant at neat concentration; aspiration hazard if swallowed; oxidation products (farnesene epoxides) may increase sensitization and must be stored under antioxidant protection.

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Concern Level: Moderate

Regulatory Flags

potential-allergen fragrance-component

Frequently Asked Questions

Is Farnesene safe in cosmetics?

GHS Category 2 skin irritant and Category 2A eye irritant at neat concentration; aspiration hazard if swallowed; oxidation products (farnesene epoxides) may increase sensitization and must be stored under antioxidant protection. The EU classifies Farnesene as "permitted". Safety rating: GOOD.

Is Farnesene allowed in the EU?

Farnesene EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Farnesene do in cosmetics?

Farnesene functions as: Fragrance ingredient, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 502-61-4 (mixture of isomers).

What is the Margin of Safety for Farnesene?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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