Good Cosmetic Ingredient

CI 75125 (Lycopene)

INCI: CI 75125

CAS Number

502-65-8

Function

Colorant. Natural carotenoid pigment extracted from tomatoes (Lycopersicon esculentum), also known as Lycopene and Natural Red 73. Imparts red-orange coloration to cosmetic products. Oil-soluble dye from the carotene family. Also designated food colorant E160d. Permitted EU colorant subject to purity criteria per Commission Directive 95/45/EC.

Safety Rating

GOOD

Regulatory Status

🇪🇺 EU Status permitted

🇺🇸 US Status restricted

US Notes FDA permanently lists Tomato Lycopene Extract (CAS 502-65-8) as a color additive exempt from certification under 21 CFR 73.585 for use in foods only. CI 75125 as a standalone cosmetic colorant is not listed in 21 CFR Parts 73 or 74 for cosmetic use. US cosmetic labeling as a color additive is not formally supported; lycopene may be used as a functional ingredient but not as a listed color additive for cosmetics.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)

not established

Dermal Absorption

negligible

Sensitization

none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

CI 75125 (Lycopene) is a naturally occurring carotenoid pigment permitted in EU cosmetics under Annex IV with established purity criteria. FDA approves lycopene extract only for food coloring; no formal US cosmetic colorant listing exists. Safety profile is excellent given extensive dietary exposure history and natural origin.

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Concern Level: Low

Regulatory Flags

natural-colorant carotenoid eu-annex-iv oil-soluble tomato-derived e160d food-grade-origin us-fda-food-only no-fda-cosmetic-color-listing fda_food_additive eu_cosing_listed

Frequently Asked Questions

Is CI 75125 (Lycopene) safe in cosmetics?

Is CI 75125 (Lycopene) allowed in the EU?

CI 75125 (Lycopene) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does CI 75125 (Lycopene) do in cosmetics?

CI 75125 (Lycopene) functions as: Colorant. Natural carotenoid pigment extracted from tomatoes (Lycopersicon esculentum), also known as Lycopene and Natural Red 73. Imparts red-orange coloration to cosmetic products. Oil-soluble dye from the carotene family. Also designated food colorant E160d. Permitted EU colorant subject to purity criteria per Commission Directive 95/45/EC.. It is classified as a cosmetic ingredient in our database. CAS number: 502-65-8.

What is the Margin of Safety for CI 75125 (Lycopene)?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check CI 75125 (Lycopene) compliance across multiple jurisdictions:

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82 Allergen Checker

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Substance Compliance

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MoS Calculator

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Heavy Metal Limits

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