Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for Ferric Chloride. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 1000 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 336 mg/kg bw/day | oral | rat | Carcinogenicity | COSMOS_DB |
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Expert Verdict
GHS Hazard: H302 (harmful if swallowed), H315 (skin irritant), H318 (serious eye damage); corrosive at working concentrations; concentration must be strictly controlled; requires robust risk assessment in CPSR; pH-dependent irritation; not suitable for leave-on products at standard concentrations
Regulatory Flags
Frequently Asked Questions
Is Ferric Chloride safe in cosmetics?
GHS Hazard: H302 (harmful if swallowed), H315 (skin irritant), H318 (serious eye damage); corrosive at working concentrations; concentration must be strictly controlled; requires robust risk assessment in CPSR; pH-dependent irritation; not suitable for leave-on products at standard concentrations The EU classifies Ferric Chloride as "permitted". Safety rating: POOR. 2 toxicological study endpoint(s) are available in our database.
Is Ferric Chloride allowed in the EU?
Ferric Chloride EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Ferric Chloride do in cosmetics?
Ferric Chloride functions as: Astringent. It is classified as a cosmetic ingredient in our database. CAS number: 7705-08-0.
What is the Margin of Safety for Ferric Chloride?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Ferric Chloride?
The NOAEL (No Observed Adverse Effect Level) for Ferric Chloride is 1000 mg/kg bw/day based on a Subchronic study via oral route in rat. A total of 2 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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