Fibronectin

INCI: FIBRONECTIN

CAS Number
86088-83-7
Function
Skin conditioning agent
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted, no CFR restriction; CIR reviewed (safe in present practices of use)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Protein origin (human/bovine) requires BSE/TSE sourcing documentation; batch-to-batch variability present; biological origin must be declared per EU GMP.

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Concern Level: Low

Frequently Asked Questions

Is Fibronectin safe in cosmetics?

Protein origin (human/bovine) requires BSE/TSE sourcing documentation; batch-to-batch variability present; biological origin must be declared per EU GMP. The EU classifies Fibronectin as "permitted". Safety rating: EXCELLENT.

Is Fibronectin allowed in the EU?

Fibronectin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Fibronectin do in cosmetics?

Fibronectin functions as: Skin conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: 86088-83-7.

What is the Margin of Safety for Fibronectin?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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