Is Geranyl Butyrate safe in cosmetics?
Geranyl Butyrate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Geranyl Butyrate
Also known as: Butanoic acid, (2E)-3,7-dimethyl-2,6-octadien-1-yl ester, Butanoic acid, 3,7-dimethyl-2,6-octadienyl ester, (E)-, Butyric acid geranyl ester, 3,7-Dimethyl-2,6-octadienyl butanoate, (E)-, 3,7-Dimethyl-2,6-octadien-1-yl butanoate, trans- (+10 more)
INCI: GERANYL BUTYRATE
Geranyl Butyrate (CAS 106-29-6) is a cosmetic cosmetic ingredient functioning as Fragrance. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety, pharmaceutical, and food safety data.
View industrial chemical safety profile for CAS 106-29-6 →
Auto-generated CPSR Part A draft with source citations
Chemistry & Identifiers
IUPAC Name
[(2E)-3,7-dimethylocta-2,6-dienyl] butanoate
InChIKey
ZSBOMYJPSRFZAL-JLHYYAGUSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted; FEMA GRAS (FEMA 2512); FDA approved food flavoring
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Geranyl Butyrate.
Calculate MoS for your specific formulation with the MoS Calculator.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 2592 | - | - |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Additional Ingredient Properties
1 property record from structured ingredient metadata.
fragrance_ifra
{"cas_number": "106-29-6", "ifra_amendment_number": "49", "ifra_restriction_type": "Restricted", "ifra_max_use_level_category_1_pct": "0.13", "ifra_max_use_level_category_4_pct": "2.1", "ifra_max_use_level_category_7_pct": "0.30", "ifra_max_use_level_category_11_pct": "0.060", "eu_allergen_declaration_required": "No", "eu_26_allergens_list": "No", "sccs_opinion_available": "Yes", "sensitization_po…
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (2)
JECFA Number
66
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
GERANYL BUTYRATE | 2002 | No safety concern at current levels of intake when used as a flavouring agent | Secondary components do not raise a safety concern | TRS 913-JECFA 59/111 | FAS 40-JECFA 49/329 (1997)
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
No specific technical function
Regulatory List Membership (3)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for Geranyl Butyrate.
Regulatory Flags
potential-allergen
fragrance-component
ifra_fragrance
fda_food_additive
jecfa_safe
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Geranyl Butyrate by CAS number or substance name.
Studies
3
Lowest NOAEL
908.333312988 mg/kg bw/day
Highest NOAEL
908.333312988 mg/kg bw/day
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip
Known Synonyms
Butanoic acid, (2E)-3,7-dimethyl-2,6-octadien-1-yl ester
Butanoic acid, 3,7-dimethyl-2,6-octadienyl ester, (E)-
Butyric acid geranyl ester
3,7-Dimethyl-2,6-octadienyl butanoate, (E)-
3,7-Dimethyl-2,6-octadien-1-yl butanoate, trans-
3,7-Dimethyl-2,6-octadienyl butyrate, (E)-
trans-3,7-Dimethyl-2,6-octadien-1-yl butyrate
EINECS 203-381-3
FEMA No. 2512
Geraniol butyrate
Geranyl butanoate
Geranyl n-butyrate
NSC 46146
2,6-Octadien-1-ol, 3,7-dimethyl-, butyrate, (E)-
UNII-69AVH8L7KL
Chemical Function
Fragrance
No specific technical function
Flavouring and nutrient
Regulatory Lists
Australia; Food and drug - smoking-related products
IFRA Transparency
Europe
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
consumer_product
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical and food safety data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3187344
SOURCE
EFSA / FDA GRAS
food_additives
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
GERANYL BUTYRATE
ADI
No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
Food Category
flavoring
Frequently Asked Questions
Is Geranyl Butyrate allowed in the EU?
Geranyl Butyrate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Geranyl Butyrate do in cosmetics?
Geranyl Butyrate functions as: Fragrance. It is classified as a cosmetic ingredient in our database. CAS number: 106-29-6.
Is Geranyl Butyrate used outside cosmetics?
Geranyl Butyrate also appears in industrial chemical safety, pharmaceutical, and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Geranyl Butyrate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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